Research Topic: wound healing

Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

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This research explores how medicinal mushrooms, especially a species called Cerrena unicolor, could be used to improve human health through functional foods and dietary supplements. These mushrooms contain natural compounds that fight cancer, bacteria, viruses, and free radicals that damage our cells. Scientists have found that incorporating these mushroom extracts into foods, particularly dairy products, could create powerful health-promoting foods that help with cancer treatment, diabetes management, and wound healing.

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Isolation, Characterization, and Wound-Healing Potential of β-D-Glucan from Lycoperdon pyriforme Schaeff

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Researchers isolated and studied a compound called β-D-glucan from puffball mushrooms (Lycoperdon pyriforme) that have been traditionally used to heal wounds and stop bleeding. Laboratory tests showed this compound safely promotes the movement and growth of skin cells that help wounds close without harming red blood cells, and it actually helps blood clot faster. These findings support the traditional use of this mushroom and suggest it could be developed into a new natural wound-healing treatment.

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Vulnerability of Walnut Pruning Wounds to Fungal Trunk Pathogens and Seasonal Conidial Dynamics of Botryosphaeriaceae in the Maule Region, Chile

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When walnut trees are pruned, the resulting wounds are exposed to dangerous fungi that can cause branch die-back and significantly reduce crop yield. This research found that freshly cut pruning wounds are most vulnerable to infection, especially from aggressive fungi like Diplodia mutila, but this vulnerability decreases over time. The fungi spread their spores mainly during wet winter months when rainfall and humidity are high, so timing pruning operations to avoid these periods and protecting wounds with fungicides could substantially reduce disease losses in walnut orchards.

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Biofilms and Chronic Wounds: Pathogenesis and Treatment Options

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Chronic wounds, such as diabetic foot ulcers and burn injuries, are often complicated by bacterial and fungal biofilms—protective communities of microorganisms that resist antibiotics and delay healing. This review summarizes how biofilms form, why they are difficult to treat with standard approaches, and discusses new therapeutic strategies. While debridement and antiseptics remain important, combining them with novel treatments like bacteriophages, enzyme therapies, and nanotechnology offers better chances for healing these stubborn wounds.

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High Efficiency In Vitro Wound Healing of Dictyophora indusiata Extracts via Anti-Inflammatory and Collagen Stimulating (MMP-2 Inhibition) Mechanisms

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This study examines bamboo mushroom extracts for their ability to promote skin wound healing. Researchers tested three different parts of immature bamboo mushrooms and found that the core extract was particularly effective at reducing inflammation and preventing excessive collagen breakdown, which helps wounds heal properly without excessive scarring. The extract performed as well as or better than standard pharmaceutical agents, suggesting it could be a promising natural ingredient for wound healing products.

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Polysacharide of Agaricus blazei gel mitigates bone necrosis in model of the jaws related to bisphosphonate via Wnt signaling

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This study tested whether a gel made from Agaricus blazei mushroom could help repair jaw bone damage caused by bisphosphonate medications (used to treat bone loss). Using a rat model, researchers found that the mushroom gel significantly improved bone healing by activating biological pathways that promote bone-forming cell growth and activity. The treatment increased the number of living bone cells, improved bone quality, and reduced bone death and tissue damage. These promising results suggest the mushroom extract could become a helpful treatment to prevent or manage jawbone damage in patients taking bisphosphonate medications.

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