Research Topic: traditional Chinese medicine

Impact of Cordyceps sinensis on coronary computed tomography angiography image quality and renal function in a beagle model of renal impairment

This study tested whether a traditional mushroom supplement called Cordyceps sinensis could protect kidney function in dogs undergoing heart imaging tests that use contrast dye. Researchers found that dogs receiving Cordyceps sinensis combined with lower doses of contrast dye maintained good image quality while showing better kidney function afterward compared to controls receiving conventional contrast doses without the supplement. Advanced imaging techniques confirmed that Cordyceps sinensis helped protect kidney tissue from damage caused by the contrast material.

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Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

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Recent Advances in the Use of Ganoderma lucidum and Coriolus versicolor Mushrooms to Enhance the Anticancer Efficacy of EGFR-Targeted Drugs in Lung Cancer

This review explores how two medicinal mushrooms traditionally used in Asian medicine—Lingzhi and Yunzhi—can enhance the effectiveness of lung cancer drugs (EGFR-TKIs) and help overcome drug resistance. These mushrooms contain special compounds that can fight cancer in multiple ways, boost the immune system, and reduce side effects. The research suggests that combining these mushrooms with standard cancer treatments may improve outcomes for lung cancer patients.

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Sporoderm-removed ganoderma lucidum spore powder (S-GLSP) alleviates neuroinflammation injury by regulating microglial polarization through inhibition of NLRP3 inflammasome activation

Researchers found that sporoderm-removed Ganoderma lucidum spore powder (S-GLSP) protects against Alzheimer’s disease by reducing brain inflammation. The supplement works by shifting immune cells in the brain called microglia from a harmful pro-inflammatory state to a protective anti-inflammatory state. This is accomplished by blocking the NLRP3 inflammasome, a key trigger of brain inflammation. In animal and cell studies, S-GLSP improved memory, reduced neuronal damage, and decreased harmful tau protein accumulation.

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Oxidative Stress in Spinocerebellar Ataxia Type 3 and Its Attenuation by Herbal Remedies in Traditional Chinese Medicine: A Systematic Review

Spinocerebellar ataxia type 3 is a serious brain disease that causes movement problems and gets worse over time. Current medications help but often have unpleasant side effects. This review examined fifteen traditional Chinese herbal remedies that show promise in protecting nerve cells from damage caused by oxidative stress, a harmful chemical process in the body. These herbs work through multiple protective mechanisms and may eventually be tested in patients.

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Identification, biological characteristics, and screening of control agents against root rot of Ardisia crenata Sims in China

Researchers identified a fungus called Fusarium cugenangense as the cause of root rot disease in Ardisia crenata, a valuable traditional Chinese medicinal plant. The disease was affecting 25-35% of plants in Chongqing farms and damaging their roots. Scientists tested various pesticides and found that fluazinam chemical spray and zhongshengmycin biological spray were the most effective at stopping the fungus, providing farmers with effective treatment options.

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Introduction to Traditional Medicine and Their Role in Prevention and Treatment of Emerging and Re-Emerging Diseases

This article explores how traditional medicine systems like Ayurveda and Chinese Medicine can help prevent and treat infectious diseases, including COVID-19. These ancient healing systems use natural herbs and lifestyle changes to boost immunity and fight infections more holistically. Scientific evidence shows that natural compounds like curcumin from turmeric have real antiviral and anti-inflammatory properties. By combining traditional knowledge with modern research, we may develop better treatments for emerging diseases.

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Research on the Action and Mechanism of Pharmacological Components of Omphalia lapidescens

Omphalia lapidescens, a medicinal fungus used in traditional Chinese medicine, contains multiple bioactive compounds with promising health benefits. These compounds can fight parasitic infections, inhibit cancer cell growth, reduce inflammation, and provide antioxidant protection. While clinical use shows benefits especially for gastric cancer when combined with chemotherapy, more research is needed to understand how these compounds work and to improve cultivation and production methods.

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Identifying Key Pathogens and Effective Control Agents for Astragalus membranaceus var. mongholicus Root Rot

Astragalus (a valuable traditional Chinese herb) often develops root rot disease caused by harmful fungi. Researchers identified the specific fungi causing this disease and tested various chemical fungicides and beneficial bacteria to control it. Carbendazim fungicide and a biocontrol bacterium called KRS006 proved most effective, suggesting a combination approach could protect this important medicinal plant from disease.

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Mycorrhizal fungus BJ1, a new species of Tulasnella sp.: its biological characteristics and promoting effect on seed germination of Bletilla striata

Researchers discovered a new type of fungus called Tulasnella sp. BJ1 that forms beneficial partnerships with Bletilla striata, a traditional Chinese medicinal plant. When this fungus was used with the plant’s seeds, germination rates and seedling growth improved significantly compared to seeds grown alone. The fungus helps by producing growth-promoting substances like plant hormones and breaking down nutrients that the developing plants can absorb. This finding offers a practical method to grow more B. striata plants efficiently for medicinal use.

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