traditional Chinese medicine – Page 2

Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity

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This study investigated fermenting water chestnut shells with a medicinal mushroom called Ganoderma sinense to create a more potent health product. Under optimal fermentation conditions, the resulting material showed significantly improved immune-boosting and antioxidant properties when tested in laboratory cells. The fermentation process changed the structure of polysaccharides and increased beneficial compounds, potentially transforming agricultural waste into a valuable functional food or supplement.

Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

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Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

The Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence

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This review explores how natural products from traditional Chinese medicine may help treat chronic kidney disease by targeting two key aging processes: autophagy (cellular self-cleaning) and cellular senescence (cellular aging). Common natural compounds like curcumin, green tea extract, and Astragalus have shown promise in protecting kidney function and reducing harmful inflammation. While these natural treatments show potential as complementary therapies alongside mainstream medicines, more clinical research is needed to confirm their effectiveness and determine optimal dosages.

Bibliometric analysis of traditional Chinese medicine for viral infections through immune modulation (2015–2025)

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This research analyzed over 3,300 scientific papers published between 2015-2025 to understand how traditional Chinese medicine helps fight viral infections by boosting the immune system. The study found that research on this topic has grown significantly, especially during disease outbreaks like COVID-19, with China leading in research publications. Key findings show that traditional Chinese herbal compounds work through multiple mechanisms including directly fighting viruses, reducing excessive inflammation, and enhancing vaccine effectiveness. The research points toward promising future applications of traditional Chinese medicine when combined with modern medical approaches.

The safety and efficacy of Houtou Jianweiling tablet in patients with chronic non-atrophic gastritis: a double-blind, non-inferiority, randomized controlled trial

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This study tested a traditional Chinese herbal medicine called Houtou Jianweiling Tablet against omeprazole, a common stomach medication, for treating chronic stomach inflammation. The herbal tablet worked just as well as the conventional drug at relieving stomach pain, bloating, and reducing harmful bacteria, while being very safe with almost no side effects. This suggests that people with mild to moderate stomach inflammation could use this natural herbal alternative instead of, or alongside, conventional medications.

Emerging paradigms for target discovery of traditional medicines: A genome-wide pan-GPCR perspective

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Traditional medicines from plants, animals, and fungi contain chemical compounds that can interact with specific proteins in our cells called G protein-coupled receptors (GPCRs). These receptors control many important body functions and are targeted by about one-third of all FDA-approved medications. This review explains how scientists are discovering new therapeutic compounds from traditional medicines by systematically screening them against the complete library of human GPCRs, using advanced techniques to identify which compounds bind to which receptors. Famous examples include morphine from poppies for pain relief and compounds from ginseng that help regulate blood sugar.

Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

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This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

The Active Components of Traditional Chinese Medicines Regulate the Multi-Target Signaling Pathways of Metabolic Dysfunction-Associated Fatty Liver Disease

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This comprehensive review examines how traditional Chinese medicine ingredients can treat fatty liver disease through multiple biological pathways simultaneously. Unlike conventional drugs that target a single pathway, TCM compounds address the complex, interconnected causes of the disease including fat accumulation, inflammation, and tissue damage. The research identifies dozens of effective herbal compounds and proposes a new framework for designing TCM treatments tailored to individual patient needs.

Traditional Chinese Medicine for Hashimoto’s Thyroiditis: Focus on Selenium and Antioxidant Phytochemicals

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Hashimoto’s thyroiditis is a common autoimmune thyroid disease that often leads to symptoms like fatigue and reduced quality of life. While standard treatment uses thyroid hormone replacement, it doesn’t address the underlying inflammation and oxidative stress. This review explores how traditional Chinese medicine approaches, often combined with selenium, may help reduce thyroid antibodies and improve symptoms through their antioxidant and anti-inflammatory properties.

Screening of active components of Ganoderma lucidum and decipher its molecular mechanism to improve learning and memory disorders

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Researchers used computer analysis and laboratory experiments to understand how a medicinal mushroom called Ganoderma lucidum (reishi) helps improve memory and learning problems. They identified ten key active ingredients in the mushroom that work together to reduce inflammation in the brain and protect nerve cells. The most important ingredient appears to be a compound called β-sitosterol, which helps prevent memory loss similar to effects seen in Alzheimer’s disease.

Research Topic: traditional Chinese medicine