Research Topic: sepsis

mGem: Sepsis and antimicrobial resistance in the context of advanced HIV disease

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This review examines how serious infections (sepsis) from bacteria and fungi affect people with advanced HIV disease, particularly in hospitals. The infections have become more dangerous due to antimicrobial resistance, and many cases go undiagnosed because of limited laboratory capabilities. The paper calls for better diagnostic tools and treatment strategies tailored to resource-limited settings where most advanced HIV disease cases occur.

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Clinical insights into mixed Candida and bacterial bloodstream infections: a retrospective cohort study

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This study found that when both Candida fungus and bacteria are present together in a patient’s bloodstream, the outcome is much more serious than when only Candida is present. Among patients with these mixed infections, over 60% died within 30 days compared to about 52% for those with only Candida. The research shows that giving the right antibiotics early and following proper treatment guidelines can significantly improve survival chances in these severe, life-threatening infections.

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