Research Topic: psychiatric applications

Effects of classical psychedelics on implicit and explicit emotional empathy and cognitive empathy: a meta-analysis of MET task

This study compiled data from multiple research studies to understand how classical psychedelics like LSD, psilocybin, and ayahuasca affect empathy—the ability to understand and share others’ feelings. The findings show these substances significantly increase emotional empathy, helping people feel more connected to others’ emotions. However, they don’t appear to affect cognitive empathy, which is the mental ability to understand what others are thinking. These results suggest psychedelics may have therapeutic potential for improving social connection and emotional understanding.

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Trajectory of Antidepressant Effects after Single- or Two-Dose Administration of Psilocybin: A Systematic Review and Multivariate Meta-Analysis

This comprehensive analysis of 10 clinical trials shows that psilocybin, a compound from magic mushrooms, can rapidly reduce depression symptoms starting within one day of administration and maintain these benefits for up to 6 months. Higher doses and two treatment sessions produced better results than single lower doses. While psilocybin did raise blood pressure temporarily, it was generally well-tolerated with dropout rates similar to placebo.

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