This study followed 56 patients with familial adenomatous polyposis (FAP), a genetic condition causing multiple polyps in the digestive tract, for 10 years. Patients who continuously took Adipol, a supplement made from milk thistle, flaxseed, and oat fiber, had significantly fewer and smaller polyps in the duodenum (part of the small intestine) compared to those who didn’t take it. The supplement appeared safe and well-tolerated over the entire 10-year period, making it a promising preventive strategy for FAP patients.