Research Topic: Pathology

PcLRR-RK3, an LRR receptor kinase is required for growth and in-planta infection processes in Phytophthora capsici

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Researchers studied a specific protein called PcLRR-RK3 that helps Phytophthora capsici, a disease-causing organism, infect plants. By reducing the amount of this protein, they found that the pathogen became much weaker, could not grow as well, and could not successfully infect plants. This protein sits on the surface of the pathogen’s cells and acts like a communication tool that the organism needs to develop and cause disease.

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Case Report: Liquid-based cytology diagnosis of pulmonary mucormycosis

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A 41-year-old man with diabetes developed a serious lung infection caused by mucormycosis, a rare and dangerous fungus. Doctors diagnosed the infection using liquid-based cytology, a technique that examines fluid from the lungs under a microscope, which proved more effective than traditional methods. Treatment with antifungal medications helped stabilize the patient’s condition, and he remained healthy during an eight-month follow-up. This case highlights how advanced diagnostic techniques can help doctors quickly identify and treat severe fungal infections.

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Disseminated Lichtheimia ramosa infection in a Japanese Black calf

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A young beef calf developed severe diarrhea and fever that did not respond to multiple antibiotics. The calf had an underdeveloped immune system (missing thymus gland) and was treated with many antibiotics and steroids, which weakened its immune system further. After death, examination revealed the calf had a widespread fungal infection caused by Lichtheimia ramosa in the liver and digestive tract, representing the first documented case of this type in Japanese Black cattle.

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Stonebrood Disease—Histomorphological Changes in Honey Bee Larvae (Apis mellifera) Experimentally Infected with Aspergillus flavus

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Researchers studied how a rare fungal disease called stonebrood affects honey bee larvae by infecting them with the fungus Aspergillus flavus. They found that the fungus establishes in the bee’s gut within 24 hours and kills the larvae within two days, likely through production of toxic compounds. The study reveals three stages of infection progression and highlights why beekeepers need protection when handling infected colonies.

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First Report of Trametes hirsuta, Causal Agent White Rot in Avocado Trees Grown in the State of Michoacán, México

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Scientists in Mexico discovered a wood-rotting fungus called Trametes hirsuta infecting avocado trees for the first time. The fungus causes white rot disease that damages tree wood and can kill trees within 3-5 years. Researchers found the fungus on 60% of avocado trees in Michoacán orchards and confirmed its destructive effects through laboratory tests. Treatment options include pruning infected areas and applying antifungal chemicals or biological control agents.

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