Research Topic: Parasitology

Effect of Selected Entomopathogenic Fungal Species on Embryonic Development of Ascaris suum (Nematoda)

Researchers tested five types of fungi that naturally attack insects to see if they could control Ascaris roundworm eggs that contaminate pig farms and pose health risks. While none of the fungi directly killed the eggs, two species (Isaria fumosorosea and Metarhizium robertsii) successfully slowed egg development and showed potential for controlling parasites. These fungi appear to work by producing toxic compounds and enzymes rather than by penetrating the egg shells directly.

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Fungal keratitis complicating the diagnosis of Acanthamoeba keratitis

A 42-year-old farmer presented with a severe eye infection that was initially misdiagnosed as a viral infection caused by herpes simplex virus. When antiviral treatment failed, doctors discovered the patient had a fungal infection caused by Fusarium. However, advanced testing revealed she actually had a dual infection with both the fungus and a microscopic parasite called Acanthamoeba. The patient required corneal transplant surgery and combination therapy with multiple medications to control the infection and preserve vision.

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Not everything that wiggles is a worm: Pseudoparasites in parasitology

When examining patient samples under a microscope, parasitologists must be careful to distinguish real parasites from artifacts that only look like parasites. Items such as pollen, plant fibers, yeast, and food remnants can closely resemble parasitic organisms and lead to incorrect diagnoses and unnecessary treatment. By using proper training, multiple diagnostic techniques, and careful morphological evaluation, healthcare professionals can avoid these diagnostic errors and ensure accurate patient care.

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Rapid onsite evaluation in cytomorphology of Hydatidosis: A useful adjunct to diagnosis

A 45-year-old woman was found to have a cyst in her liver caused by a parasitic tapeworm infection (hydatidosis). Doctors used quick examination techniques on fluid from the cyst, including special stains, to confirm the diagnosis before surgery. This rapid diagnosis was important to prevent serious complications. The case shows how simple, cost-effective examination methods can effectively diagnose parasitic infections.

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Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa

This study surveyed laboratory facilities across Africa to understand what infectious disease tests are available. Researchers found that basic tests like bacterial identification are common, but advanced tests for viruses (other than HIV) and fungi are less available. The study highlights the need for investment in laboratory infrastructure to improve disease diagnosis and help countries respond to health emergencies.

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Gastrointestinal Parasites, Ectoparasites, and Fungi in Rabbits Attending Clinical Consultations and from Private Owners and Breeders in Portugal

This study examined parasites, mites, and fungi found in Portuguese rabbits by testing samples from 72 animals at veterinary clinics and private homes. More than half of the rabbits carried intestinal parasites, most commonly coccidia and Cryptosporidium, though few showed obvious illness. Regular cleaning of rabbit housing and proper deworming with fenbendazole significantly reduced parasite infection rates, highlighting the importance of good hygiene practices.

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Multicenter performance evaluation of the “quanty TOXO (RH region)” kit (Clonit) for molecular diagnosis of toxoplasmosis

Researchers from seven French hospitals tested a commercial DNA test kit called “quanty TOXO” that detects Toxoplasma gondii, a parasite causing serious infections in pregnant women and people with weakened immune systems. The kit performed well overall, correctly identifying infection in nearly 95% of positive cases and showing no false positives. However, the test sometimes missed infections when parasite levels were very low, suggesting doctors should run tests twice to increase detection chances.

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A carnivorous mushroom paralyzes and kills nematodes via a volatile ketone

Scientists discovered that oyster mushrooms kill parasitic worms using a toxic gas stored in tiny bulb-shaped structures called toxocysts. The toxin is a common chemical called 3-octanone that ruptures the worms’ cell membranes, causing calcium to flood into cells and leading to rapid paralysis and death. This ‘nerve gas in a lollipop’ strategy could inspire new ways to control parasitic worms in agriculture and medicine.

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Nosocomial Diarrhea Distribution by Cryptosporidium in Isfahan

Researchers tested 217 patients who developed diarrhea in a hospital in Isfahan, Iran to see if a parasite called Cryptosporidium was responsible. Using advanced DNA testing, they found the parasite in only 2 out of 217 patients (less than 1%). This suggests that while this parasite can spread in hospitals, it is not a major cause of diarrhea in this particular hospital, which likely has good hygiene practices.

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