Research Topic: Mycoviruses

Genomic insights reveal community structure and phylogenetic associations of endohyphal bacteria and viruses in fungal endophytes

Fungi living inside healthy plant leaves contain communities of bacteria and viruses. Researchers studied these microbial passengers in fungi from American beech leaves and found that bacteria show patterns of preference for specific fungal types, while viruses are less diverse and mostly DNA-based rather than RNA-based. Understanding these microbial relationships helps explain how fungi interact with plants and could potentially improve biological control strategies.

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Mycoviruses: Antagonistic Potential, Fungal Pathogenesis, and Their Interaction with Rhizoctonia solani

This comprehensive review explores how viruses that infect fungi, called mycoviruses, could help farmers control rice diseases. Rice sheath blight caused by the fungus Rhizoctonia solani causes significant crop losses worldwide. Scientists have discovered that certain mycoviruses can weaken this pathogenic fungus, making them promising biological alternatives to chemical fungicides that can harm the environment and encourage disease resistance.

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Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

A virus that infects the fungus Aspergillus fumigatus makes the fungus more dangerous by helping it survive stress and resist immune cell attack. When researchers removed the virus from the fungus, it became weaker and less harmful to infected mice. Treating infected mice with an antiviral drug called ribavirin reduced the virus, lowering fungal burden and improving survival, suggesting that targeting fungal viruses could be a new way to treat serious fungal infections.

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Heterologous expression of the hypovirus CHV1-EP713 full-length cDNA in Botrytis cinerea: transformation with Agrobacterium tumefaciens and evaluation of changes in the fungal phenotype

Researchers successfully introduced a virus from chestnut blight fungus into gray mold fungus to reduce its ability to cause disease. The transformed fungus grew slower, produced fewer spores, and caused less damage to plants. This discovery suggests viruses could be used as natural biological control agents to protect crops from fungal diseases.

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A mycovirus shaped insect-pathogenic and non-pathogenic phenotypes in a fungal biocontrol agent

Scientists discovered that a virus living inside a beneficial fungus is responsible for the fungus’s ability to kill insect pests. When they removed the virus, the fungus completely lost its ability to penetrate and infect insects through their skin, but could still cause infection if injected directly into the insect’s body. This finding suggests that the virus controls a key enzyme needed for the fungus to break through the insect’s protective outer layer, opening new possibilities for creating more effective biological pest control agents.

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A mycovirus enhances fitness of an insect pathogenic fungus and potentially modulates virulence through interactions between viral and host proteins

Scientists discovered a virus that infects Beauveria bassiana, a fungus used to control pests naturally. This virus actually helps the fungus by making it produce more spores, survive harsh conditions like sunlight and heat, and kill target insects faster. The virus does this by interacting with specific fungal proteins that control reproduction, stress response, and virulence. This discovery could lead to better biological pest control products that are more effective and reliable than current options.

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