Research Topic: Mycology

Identification and potential of the hyperparasite Acremonium persicinum as biocontrol agent against coffee leaf rust

Coffee plants are severely damaged by a fungal disease called coffee leaf rust that destroys leaves and can reduce harvests by over 70%. Scientists in China discovered a beneficial fungus called Acremonium persicinum that acts as a natural enemy to the rust-causing fungus, essentially eating and destroying it. Laboratory tests showed this beneficial fungus prevented rust infection in 91% of cases and completely stopped the disease from spreading when applied to infected coffee leaves. This natural biological control offers an environmentally friendly alternative to chemical pesticides for protecting coffee crops.

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Two new species of Entoloma subg. Cyanula sect. Asprella (Entolomataceae, Agaricales) from subtropical regions of China

Scientists have identified two new mushroom species in China belonging to the genus Entoloma. These small blue and magenta mushrooms, named E. qingluan and E. zilin, were discovered in subtropical forests of Fujian and Zhejiang provinces. Using microscopic examination and genetic analysis, the researchers confirmed these were previously unknown species and provided detailed descriptions for scientific identification and classification.

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Development of a molecular genetics and cell biology toolbox for the filamentous fungus Diplodia sapinea

Scientists have developed new tools to study a fungus called Diplodia sapinea that damages pine trees around the world. They created a method to genetically modify this fungus and tag its cell nuclei with a red fluorescent marker so they can track the infection process. They also developed a simple way to test infections using young pine seedlings in the laboratory instead of large greenhouse setups. Using these new tools together, researchers can now watch in real-time how the fungus grows inside infected pine plants, which will help develop better ways to protect forests.

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Invasive nasal and paranasal mucormycosis in a patient with severe dengue fever and multiple risk factors: A case report and literature review

A 50-year-old woman in Vietnam developed a rare and deadly fungal infection called mucormycosis while recovering from dengue fever. She had weakened immunity from taking steroids for other conditions and from the dengue virus itself. The infection caused black, dead tissue to rapidly spread in her nose and around her eye. Despite treatment with antifungal medications, the infection progressed, and she died within days. The case shows how important it is to watch for dangerous opportunistic infections in dengue patients, especially those already dealing with weakened immune systems.

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Digging into the evolutionary history of the fungus-growing-ant symbiont, Escovopsis (Hypocreaceae)

Researchers studied fungi called Escovopsis that live in ant colonies and interact with the fungi that ants farm for food. By examining 309 fungal samples from across Central and South America, they discovered that these fungi originated 57 million years ago but only started living with the ants about 38 million years ago. Over time, Escovopsis evolved to grow faster and reproduce more efficiently, likely helping it survive in the ant colony environment.

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A case report of childhood onychomycosis caused by the rare yeast Kodamaea ohmeri

A 5-year-old girl in Vietnam developed a nail infection caused by a rare yeast called Kodamaea ohmeri, which typically affects adults with diabetes or weak immune systems. The infection, appearing as white discoloration on the nails, was successfully treated with a topical antifungal cream applied three times daily for one month. This is the first reported case of this rare yeast causing nail infection in a child in Vietnam, and it demonstrates that topical treatment can be effective for fungal nail infections in children whose nails are thinner than adults.

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Kre6-dependent β-1,6-glucan biosynthesis only occurs in the conidium of Aspergillus fumigatus

Researchers discovered that a specific sugar compound called β-1,6-glucan is found in the spore-like reproductive structures (conidia) of the fungus Aspergillus fumigatus but not in its growing filaments (mycelium). Using advanced nuclear magnetic resonance technology, they identified the KRE6 gene as responsible for making this sugar and found that removing this gene makes the fungus more vulnerable to certain chemicals that damage fungal cell walls.

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Deubiquitinase Ubp5 is essential for pulmonary immune evasion and hematogenous dissemination of Cryptococcus neoformans

This study shows that removing a fungal enzyme called Ubp5 from Cryptococcus neoformans significantly weakens the fungus and allows the body’s immune system to fight the infection more effectively. The fungus without Ubp5 loses its ability to hide from the immune system, triggering stronger protective immune responses including more T cells and beneficial inflammatory signals. This research suggests that targeting Ubp5 could be a promising strategy to help treat cryptococcal infections by enhancing the body’s natural defense mechanisms.

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Laboratory and Field Bioassays of Arthropod Pathogenic Fungi Application for the Control of the Hazelnut Big Bud Mite, Phytoptus avellanae s. l.

Hazelnut farming is threatened by small pests called big bud mites that damage buds and reduce crop production. This study tested two types of beneficial fungi as a natural pest control method, finding that Beauveria bassiana was very effective at killing these mites in both laboratory and field conditions. These fungal treatments could provide farmers with a sustainable alternative to chemical pesticides for protecting their hazelnut crops.

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