Research Topic: Mycology

First Step on the Way to Identify Dermatophytes Using Odour Fingerprints

Researchers have developed a new method to quickly identify fungal skin infections caused by dermatophytes by detecting the unique smells (volatile compounds) they produce. Instead of waiting days or weeks for culture-based tests, this approach uses advanced chemical analysis to create a fingerprint of the fungus based on its odor. The study analyzed 47 different dermatophyte strains and found that each species and even individual strains have distinctive chemical signatures, which could one day allow doctors to diagnose infections rapidly using portable devices similar to electronic noses.

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A mycovirus shaped insect-pathogenic and non-pathogenic phenotypes in a fungal biocontrol agent

Scientists discovered that a virus living inside a beneficial fungus is responsible for the fungus’s ability to kill insect pests. When they removed the virus, the fungus completely lost its ability to penetrate and infect insects through their skin, but could still cause infection if injected directly into the insect’s body. This finding suggests that the virus controls a key enzyme needed for the fungus to break through the insect’s protective outer layer, opening new possibilities for creating more effective biological pest control agents.

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Characterization of the Spatiotemporal Localization of a Pan-Mucorales–Specific Antigen During Germination and Immunohistochemistry

Researchers developed a new diagnostic test using a special antibody that can detect Mucorales fungi, which cause a serious infection called mucormycosis. The antibody glows to mark growing fungal threads in tissue samples, helping doctors identify the infection early and distinguish it from other mold infections like Aspergillus. This breakthrough could significantly improve patient outcomes by enabling faster diagnosis and treatment of this aggressive fungal disease.

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Folliculocentric tinea versicolor: a case report

A 46-year-old woman was diagnosed with an unusual presentation of tinea versicolor, a common fungal skin infection, where the fungus centered around hair follicles rather than appearing as typical patches. The condition was successfully treated with antifungal medications, though some changes persisted. The doctors noted that the patient’s history of keratosis pilaris (a common bumpy skin condition on the arms and thighs) may have contributed to this unusual follicle-focused presentation.

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Evaluation of Clinical, Microbiological Profiles and Management Patterns with Outcomes of Patients with Fungal Isolates in An Intensive Care Unit of A Tertiary Care Center: A Prospective Observational Study

This study examined fungal infections in patients staying in intensive care units at a hospital. Researchers found that diabetes was the most common risk factor, and a fungus called Candida tropicalis was the most frequently isolated organism from urine samples. Many of the fungal strains were resistant to fluconazole, a common antifungal medication, suggesting doctors need to choose different treatments based on which drugs the fungi are resistant to.

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Morphological and molecular identification of Schizophyllum commune causing storage bulb rot disease of Lanzhou edible lily in China and its biological characteristics

Researchers in China identified Schizophyllum commune as a fungal pathogen causing rot in stored edible lily bulbs, marking the first report of this disease. The fungus was identified using microscopic examination and genetic sequencing, and was shown to cause 100% infection on lily bulbs. The study found that the fungus grows best at 30°C with high humidity and darkness, providing important information for controlling this storage disease that causes significant crop losses.

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Photo Quiz: A cutaneous fungal infection with discordant biomarker results—a diagnostic challenge

A woman with advanced HIV infection presented with skin sores and respiratory symptoms that were initially suspected to be a viral infection. Testing revealed she had histoplasmosis, a serious fungal infection caused by Histoplasma capsulatum that had spread throughout her body affecting her skin, lungs, and lymph nodes. While standard tests for this fungus were negative, other fungal markers and cultures eventually confirmed the diagnosis, and she was treated with antifungal medications.

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Chlorencoelia (Leotiomycetes, Helotiales, Cenangiaceae) in New Zealand

Researchers discovered that fungi previously thought to be just two species found in New Zealand are actually three distinct species. By examining the fungi’s DNA and microscopic features, scientists identified two species new to science: Chlorencoelia australis and Chlorencoelia northlandica, plus another species originally described from Tasmania. This research shows that many fungi species thought to be widespread are actually multiple different species that look similar but are genetically distinct.

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Spectrum of Fungal Infections in Continuous Ambulatory Peritoneal Dialysis: A 20-Year Retrospective Study From a Tertiary Care Center

This study examined fungal infections in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) over 20 years at a major Indian hospital. Researchers identified various fungal species causing peritonitis, with Candida species being most common, but discovered increasingly rare fungi involved in these infections. The study found that proper identification of the specific fungus and testing for drug resistance is crucial for effective treatment, typically involving catheter removal and targeted antifungal medications.

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Morpho-phylogenetic evidence reveals novel hyphomycetous fungi on medicinal plants in Southwestern China

Researchers discovered and described 12 new species of fungi found on medicinal plants in southwestern China. By examining the fungi’s appearance under microscopes and analyzing their DNA, scientists confirmed these were previously unknown species. Some of these fungi may produce beneficial compounds while others produce toxins, highlighting the importance of understanding which fungi live on medicinal plants to ensure their quality and safety for human use.

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