Research Topic: mushroom extract

Neuroprotective Effect of Mixed Mushroom Mycelia Extract on Neurotoxicity and Neuroinflammation via Regulation of ROS-Induced Oxidative Stress in PC12 and BV2 Cells

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A mixture of three medicinal mushrooms (Phellinus linteus, Ganoderma lucidum, and Inonotus obliquus) was tested for its ability to protect nerve cells from damage. The extract successfully reduced cell death in laboratory models of neurodegeneration by reducing harmful molecules called reactive oxygen species and reducing inflammation. These results suggest the mushroom extract could potentially help prevent or slow neurological diseases like Alzheimer’s.

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Evaluation of the synbiotic effects of Saccharomyces cerevisiae and mushroom extract on the growth performance, digestive enzyme activity, and immune status of zebrafish danio rerio

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Researchers tested whether combining a yeast called Saccharomyces cerevisiae with mushroom extract could improve the health and growth of zebrafish. The combination, called a synbiotic, significantly boosted fish growth by over 70%, enhanced their digestive function, and strengthened their immune system. This natural supplement approach shows promise for improving fish farming practices without requiring antibiotics.

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Inonotus obliquus aqueous extract prevents histopathological alterations in liver induced by environmental toxicant Microcystin

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This research shows that Chaga mushroom extract can protect the liver from damage caused by microcystin, a toxic chemical produced by cyanobacteria in water. When mice were exposed to microcystin, their livers became damaged, but treating them with Chaga mushroom extract restored normal liver function and prevented cell death. The study suggests Chaga mushroom could be used as a natural supplement to prevent liver toxicity from environmental pollutants.

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In vitro Selection of Synbiotics and in vivo Investigation of Growth Indices, Reproduction Performance, Survival, and Ovarian Cyp19α Gene Expression in Zebrafish Danio rerio

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Scientists tested a combination of beneficial bacteria (Lactobacillus strains) mixed with mushroom extract as a food supplement for farmed fish. After 4 months of feeding this supplement to zebrafish, the fish grew faster, converted food more efficiently, and showed improved reproductive capability with increased egg production. The mushroom extract helped the beneficial bacteria thrive and function better, suggesting this natural supplement could improve fish farming outcomes.

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