Research Topic: molecular epidemiology

Occurrence of Pathogenic and Allergenic Molds in the Outdoor and Indoor Environment of a Major Hospital and Molecular Epidemiology of Aspergillus fumigatus in Kuwait

Researchers studied molds found in and around a major hospital in Kuwait over 17 months, collecting over 6,000 mold samples. They discovered various mold species, including some that can cause serious infections in hospital patients. Importantly, they found drug-resistant Aspergillus fumigatus strains both outdoors and inside the hospital, suggesting the environment may be a source of infection for vulnerable patients. The findings highlight the need for better monitoring and control of molds in hospital settings.

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Molecular evidence of Enterocytozoon bieneusi in arid urban landscapes of shiraz cockroaches (Blattodea), Southwest Iran: Implications for urban public health surveillance

Researchers in Shiraz, Iran found that cockroaches can carry Enterocytozoon bieneusi, a dangerous fungal parasite that causes severe diarrhea in people with weak immune systems. The study collected and tested 378 cockroaches from hospitals and public areas, discovering three positive cases. While the arid climate of Shiraz appears to limit how well these pathogens survive compared to tropical regions, the presence of parasites in hospital cockroaches poses real health risks, especially for vulnerable patients. Better pest control and sanitation in hospitals are essential to prevent spread.

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Targeted long-read sequencing analysis and antifungal susceptibility profiles of Sporothrix schenckii isolates from Thailand

This research examined a fungal infection called sporotrichosis found in Thailand, particularly in cats and humans. Scientists used advanced DNA sequencing technology to accurately identify which species of the fungus caused the infections and understand how they are related to each other. They also tested how well common antifungal medications work against these fungi, finding that some strains have become resistant to itraconazole, the main drug used to treat sporotrichosis.

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Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

This research examined dangerous mold infections (Mucormycosis) that became more common after COVID-19. Scientists identified the types of molds causing these infections in Iran by testing 116 patient samples and 65 soil samples from across the country. They tested these molds against 13 different antifungal medications to find which drugs work best. The results showed that amphotericin B and posaconazole were the most effective medications, and patient samples were more susceptible to these drugs than environmental soil samples.

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Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

This study examined dangerous mold infections called mucormycosis that became more common during the COVID-19 pandemic, particularly in Iran. Researchers tested over 180 fungal samples from patients and soil to understand which types of molds cause infections and which antifungal medicines work best against them. They found that two medicines, amphotericin B and posaconazole, were most effective, while fungi from soil samples were often more resistant to treatment than those from infected patients. This research helps doctors choose the right treatments for patients with these serious infections.

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