metabolomics – Page 4

Marine-Derived Enterococcus faecalis HY0110 as a Next-Generation Functional Food Probiotic: Comprehensive In Vitro and In Vivo Bioactivity Evaluation and Synergistic Fermentation of Periplaneta americana Extract Powder

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Scientists discovered a beneficial bacteria called Enterococcus faecalis HY0110 from bluefin tuna that could help protect gut health and fight harmful pathogens better than current probiotics. This marine bacteria produces important compounds like acetic acid that kill disease-causing bacteria, reduce inflammation in inflammatory bowel disease, and even slows cancer cell growth. When fermented with cockroach powder, it creates powerful health-boosting compounds that could make functional foods more effective for managing digestive diseases and supporting overall wellness.

Non-Targeted Metabolomics Analysis Reveals Metabolite Profiles Change During Whey Fermentation with Kluyveromyces marxianus

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Scientists fermented whey (a dairy byproduct) using a special yeast called Kluyveromyces marxianus to create a nutrient-rich food. Using advanced analysis, they found that fermentation breaks down large proteins and fats into smaller, more beneficial compounds including amino acids and omega-3 fatty acids. The fermented whey showed significant increases in health-promoting substances that could help reduce inflammation, prevent disease, and improve overall nutrition.

Low Temperature Enhances N-Metabolism in Paxillus involutus Mycelia In Vitro: Evidence From an Untargeted Metabolomic Study

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Researchers studied how a common forest fungus (Paxillus involutus) responds to cold temperatures like those found in spring and autumn. Surprisingly, even though the fungus grew slower in the cold, it actually increased its nitrogen uptake and production of amino acids, the building blocks of proteins. This suggests the fungus has special adaptation mechanisms to thrive in cold environments, which could be important for understanding how climate change might affect forest health.

Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

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Researchers studied how adding olive mill waste to mushroom growing substrate affects the beneficial compounds in two edible mushrooms. They used advanced computer analysis of chemical data to find that this waste product increases healthy compounds like hericenones while reducing potentially harmful mycotoxins. This discovery could help make mushroom farming more sustainable and produce safer, healthier mushrooms for consumers.

Volatile Organic Compounds Produced by Co-Culture of Burkholderia vietnamiensis B418 with Trichoderma harzianum T11-W Exhibits Improved Antagonistic Activities against Fungal Phytopathogens

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Scientists studied how two beneficial microorganisms (a bacterium and a fungus) work together to produce compounds that kill plant-damaging fungi. When grown together, they produced more protective compounds than when grown separately, showing promise as a natural alternative to chemical fungicides for protecting crops and stored fruits from fungal diseases.

Low Temperature Enhances N-Metabolism in Paxillus involutus Mycelia In Vitro: Evidence From an Untargeted Metabolomic Study

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This study examined how a common forest fungus (Paxillus involutus) responds to cold temperatures by analyzing its chemical composition. When kept at cold temperatures like those found in spring and autumn forests, the fungus took up and used more nitrogen for making amino acids and other nitrogen compounds, even though it grew more slowly. This suggests that cold-adapted fungi have special mechanisms to acquire nutrients efficiently in cold conditions, which may be important for how they help trees survive in changing climates.

Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

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Morel mushrooms are prized edible fungi that unfortunately degrade when repeatedly cultured in the laboratory, becoming slower-growing and less productive. Researchers used advanced genetic and chemical analysis to discover that degeneration occurs when the mushroom stops producing flavonoids, natural antioxidants that protect cells from damage. A specific gene called NR-PKS is responsible for making these protective flavonoids, and it shuts down in degraded strains. The study suggests that preservation methods using cold storage or adding antioxidants could help maintain healthy, productive morel cultures.

Omics approaches to investigate pre-symbiotic responses of the mycorrhizal fungus Tulasnella sp. SV6 to the orchid host Serapias vomeracea

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This research explores how orchid-associated fungi sense and respond to their host plants before they even make physical contact. Scientists used advanced molecular techniques to track changes in gene expression and chemical composition in Tulasnella fungal cells when exposed to orchid plants. The fungi showed significant metabolic preparation, increasing production of proteins and cellular membrane components, suggesting they are actively preparing for symbiosis. This study reveals that plant-fungus interactions begin through long-distance chemical communication before the organisms ever physically meet.

Effects of a biotechnologically produced Pleurotus sapidus mycelium on gut microbiome, liver transcriptome and plasma metabolome of broilers

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Researchers tested whether mushroom mycelium (the root structure of mushrooms) grown in large bioreactors could be used as a supplement in chicken feed as a sustainable alternative to traditional ingredients. Over 5 weeks, broilers received feed with 0%, 2.5%, or 5% mushroom mycelium, with no negative effects on growth, digestion, or overall health observed. The study suggests that this biotechnologically produced mushroom biomass is a safe and potentially sustainable feed ingredient for poultry production.

Exploring the Core Functional Microbiota Related to Flavor Compounds in Douchi from the Sichuan–Chongqing Region

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Douchi is a traditional Chinese fermented soybean product valued for its unique flavor. This research examined seven different douchi samples to understand which bacteria and fungi create the flavor compounds. The scientists found that specific microorganisms like Bacillus and Mucor produce different flavor molecules including fruity, floral, and caramel aromas. These findings can help producers select the best microorganisms to create better-tasting douchi products.

Research Topic: metabolomics