Research Topic: metabolomics

Leucocalocybe mongolica Fungus Enhances Rice Growth by Reshaping Root Metabolism, and Hormone-Associated Pathways

Researchers discovered that a special fungus called Leucocalocybe mongolica, when added to soil, significantly improves rice plant growth without requiring chemical fertilizers. Plants grown in fungus-treated soil developed more branches (tillers), had longer roots, and contained more chlorophyll, making them greener and healthier. The study revealed that the fungus works by altering soil nutrients and triggering specific genes in rice roots that boost growth-promoting hormones and improve how plants process energy.

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The Promoting Mechanism of the Sterile Fermentation Filtrate of Serratia odorifera on Hypsizygus marmoreus by Means of Metabolomics Analysis

Researchers discovered that a type of bacteria called Serratia odorifera promotes the growth of a popular edible mushroom (Hypsizygus marmoreus) through chemical signal molecules. By analyzing the mushroom’s metabolism when exposed to these bacterial signals, scientists found that the bacteria enhance the mushroom’s ability to process carbohydrates and generate energy, leading to faster mycelial growth and better fruiting. These findings could help improve mushroom farming practices by reducing growing time and increasing yields.

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Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (Agaricus bisporus)

Researchers discovered a new compound in white button mushrooms called 2-amino-4-methylbenzothiazole that activates the aryl hydrocarbon receptor, which helps regulate gut health and immunity. Using a computational approach called molecular networking to compare mushroom compounds with known beneficial substances, scientists identified this previously unknown compound and confirmed its activity in laboratory cells. This discovery demonstrates how certain mushrooms may contribute to health through specific bioactive compounds and provides a faster method for finding similar compounds in other foods.

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The Microbial Community Succession Drives Stage-Specific Carbon Metabolic Shifts During Agaricus bisporus Fermentation: Multi-Omics Reveals CAZymes Dynamics and Lignocellulose Degradation Mechanisms

This research examines how different bacteria in mushroom compost work together to break down agricultural waste during the growing process. Scientists tracked microbial communities over 15 days of fermentation, finding that early stages use bacteria specialized in breaking down plant fibers, while later stages shift to bacteria that handle more complex compounds. Understanding these microbial changes helps optimize mushroom cultivation and reduce agricultural waste.

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Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

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Hypoglycemic Effect of Edible Fungi Polysaccharides Depends on Their Metabolites from the Fermentation of Human Fecal Microbiota

Edible mushrooms like Ganoderma lucidum, cordyceps, shiitake, and poria contain beneficial compounds called polysaccharides that may help control blood sugar. When these polysaccharides are digested by beneficial gut bacteria, they produce eight special metabolites that enhance the body’s ability to use glucose and improve insulin sensitivity. The research identified specific bacteria, such as Faecalibacterium and Coprococcus, that produce these beneficial metabolites, suggesting that measuring these markers could help evaluate which mushroom polysaccharides work best for diabetes prevention.

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Screening, identification, metabolic pathway of di-n-butyl phthalate degrading Priestia megaterium P-7 isolated from long-term film mulched cotton field soil in Xinjiang

This research identifies a special bacterium called Priestia megaterium P-7 that can efficiently break down di-n-butyl phthalate (DBP), a harmful plastic chemical that accumulates in cotton field soils. Scientists found that this bacterium can completely remove DBP from contaminated soil within 20 hours under optimal conditions. By studying the bacterium’s genes and metabolism, they discovered the specific enzymes and pathways it uses to degrade DBP into harmless compounds. This finding offers a practical biological solution for cleaning up contaminated agricultural soils, particularly in Xinjiang where plastic film mulching is widely used in cotton farming.

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Glycosylation and sugar variations in tyrosol yield promising prebiotic-like effects

This study tested whether chemically modified versions of tyrosol, a natural compound found in olives and red wine, could boost beneficial gut bacteria better than the original form. Researchers gave mice three different versions: plain tyrosol, natural salidroside (tyrosol with glucose attached), and a lab-created version with galactose attached instead. The galactose version worked best, promoting the most beneficial bacteria like Bifidobacteria and reducing harmful bacteria, potentially offering health benefits similar to prebiotic supplements.

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Growth performance, meat quality, cecal microbiota and metabolomics profile of turkeys fed diets containing black soldier fly (Hermetia illucens) meal

Researchers tested using black soldier fly meal as a protein source in turkey feed to replace traditional soybean meal. Turkeys fed diets containing 5% BSF meal from mid-growth to slaughter showed better growth and weight gain with minimal changes to meat quality. The improvements appeared to be linked to beneficial changes in gut chemistry rather than changes in gut bacteria, making BSF meal a promising sustainable protein alternative for poultry farming.

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DNA Authentication and Chemical Analysis of Psilocybe Mushrooms Reveal Widespread Misdeterminations in Fungaria and Inconsistencies in Metabolites

Researchers examined museum specimens of magic mushrooms and found that many are mislabeled and don’t reliably contain the psychoactive compounds they should. The study shows that psilocybin breaks down unpredictably during storage, and these mushrooms contain thousands of unknown chemical compounds. These findings suggest that current regulations and our understanding of these mushrooms need significant updates.

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