Medicinal – Page 57

From natural laboratory to drug discovery: Chemical structures, bioactivities, and biosynthesis of meroterpenoids from Ganoderma species

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This review examines special compounds called meroterpenoids found in Ganoderma mushrooms (commonly known as Reishi). Scientists have identified over 350 of these compounds from 14 different Ganoderma species. These compounds show promise for treating various health conditions including cancer, kidney disease, diabetes, and inflammatory disorders. The researchers also propose how these compounds are made inside the mushroom, which could help scientists produce them more efficiently for medical use.

Deconstructing Psychedelic Phenomenology: A Thematic Analysis of Discrete Phases of the Psychedelic Experience

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This study examined how people describe their experiences with psychedelic drugs by analyzing personal accounts shared online. Researchers found that experiences naturally fall into three phases: preparation (where knowledge and intentions matter), the actual experience (where sensory changes, mindset, and environment shape what happens), and afterward (where lasting behavioral and attitude changes occur). The study highlights how music, nature, supportive people, and clear intentions can help guide psychedelic experiences toward positive, meaningful outcomes.

Attitudes toward psychedelics and psychedelic-assisted therapy among potential mental health service users and the general population in Australia

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This Australian study surveyed over 500 people about their views on psychedelics like psilocybin and MDMA for treating mental health conditions. Most people supported medical legalization of these substances, though many had safety concerns. Those with mental illness, those with prior psychedelic experience, and those with better knowledge of psychedelics were most supportive of their therapeutic use.

Lower-dose psycholytic therapy – A neglected approach

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This review examines psycholytic therapy, a method using lower doses of LSD or psilocybin combined with ongoing psychotherapy to help people process psychological conflicts and trauma. Developed in Europe during the 1960s-1970s and used successfully at over 30 clinics, this approach was largely abandoned when psychedelics became illegal but is now being reconsidered. Historical research shows it was effective for anxiety, depression, and personality issues in treatment-resistant patients, with safety profiles comparable to conventional therapy.

Bioactive Potential of Tocosh Supplemented with Selenium-Enriched Saccharomyces Cerevisiae Biomass

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Researchers enhanced a traditional Peruvian fermented potato food called tocosh by adding selenium-enriched yeast. This combination reduced inflammation markers in immune cells without affecting its blood sugar impact or antioxidant properties. The resulting product shows promise as a functional food that could help people manage inflammatory conditions while improving nutritional content.

Adaptive Changes and Genetic Mechanisms in Organisms Under Controlled Conditions: A Review

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Organisms adapt to their environments through changes in their genes and how genes are expressed, processes that can happen over many generations even in laboratory settings. Scientists study these adaptations in fungi, insects, and plants grown under controlled conditions to understand how evolution works over shorter timeframes. The research shows that both genetic mutations and modifications to how genes work (without changing DNA itself) drive these adaptive changes. Understanding these mechanisms helps scientists improve crop productivity, develop disease resistance, and address environmental challenges like climate change.

Short-term effects of a synbiotic diet on thyroid and sex hormones in Sarabi Dogs

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Researchers tested whether a special dog food containing beneficial bacteria (L. acidophilus) and a type of fiber (inulin) would affect hormone levels in male Sarabi dogs. Over 24 days, dogs eating this special food showed no harmful changes in thyroid or sex hormones, and all hormone levels stayed normal. This suggests the synbiotic food could potentially be used long-term in dogs without worrying about negative hormonal effects.

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

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Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

Treating job-related stress with psychedelic group therapy: a case series on group ketamine-assisted psychotherapy for healthcare workers and first responders

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Researchers tested a new group therapy approach using ketamine to help firefighters, police officers, paramedics, and healthcare workers dealing with job stress and burnout. Over seven weeks, 32 participants received three ketamine sessions combined with group therapy. The results showed significant improvements in anxiety, depression, trauma symptoms, and burnout within the group. This low-cost group approach not only helped individual symptoms but also created a supportive community where workers felt understood by others in similar situations.

ZAP-X Stereotactic Radiosurgery for Optic Nerve Sheath Meningioma: A Case Report

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A 68-year-old woman with a benign brain tumor growing around her optic nerve received cutting-edge radiation treatment called ZAP-X stereotactic radiosurgery. The treatment precisely delivered radiation beams from multiple angles to shrink the tumor by 44% over six months. The patient experienced complete relief from eye pain and pressure, with reduced bulging of the eye, while maintaining excellent safety with no complications or damage to surrounding healthy structures.

Research Topic: Medicinal