Research Topic: Medicinal

Psychedelic-assisted therapy for palliative care within a home treatment setting: A case report

A 54-year-old man with terminal throat cancer received a single dose of LSD (100 μg) as part of psychedelic-assisted therapy delivered at his home. The treatment helped him experience relief from existential distress and feelings of peace. Six months later, he was in better psychological health, more motivated to pursue meaningful activities, and had discontinued pain medications while maintaining stability. This case demonstrates that psychedelic therapy can be safely administered at home for patients with life-threatening illnesses seeking existential relief.

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The Effect of Pseudomonas putida on the Microbial Community in Casing Soil for the Cultivation of Morchella sextelata

Morel mushrooms are prized edible fungi, but growing them repeatedly in the same soil causes problems because toxic ethylene gas builds up and the soil microbiome becomes unbalanced. Scientists found that a beneficial soil bacterium called Pseudomonas putida can break down the ethylene precursor and improve the soil microbial community, making morels grow better and faster. This natural approach using microbial inoculation offers a practical solution to help farmers overcome these continuous cropping challenges.

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Screening of active components of Ganoderma lucidum and decipher its molecular mechanism to improve learning and memory disorders

Researchers used computer analysis and laboratory experiments to understand how a medicinal mushroom called Ganoderma lucidum (reishi) helps improve memory and learning problems. They identified ten key active ingredients in the mushroom that work together to reduce inflammation in the brain and protect nerve cells. The most important ingredient appears to be a compound called β-sitosterol, which helps prevent memory loss similar to effects seen in Alzheimer’s disease.

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Latest advance anti-inflammatory hydrogel wound dressings and traditional Lignosus rhinoceros used for wound healing agents

This review examines modern hydrogel wound dressings and traditional medicinal mushrooms like Lignosus rhinoceros for treating wounds. Hydrogels are water-absorbing materials that mimic natural tissue and help wounds heal by maintaining moisture, preventing infection, and promoting cell growth. Traditional mushrooms offer anti-microbial and anti-inflammatory properties that could complement modern dressing technologies for better wound healing outcomes.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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Prebiotic property of tamarind seed kernel on Bifidobacterium animalis growth and biofilm formation

This study shows that tamarind seed kernel powder acts as a prebiotic, which are foods that feed beneficial bacteria in your gut. The research found that this powder promotes the growth of Bifidobacterium animalis, a helpful probiotic bacteria, and helps it form protective biofilms that adhere to intestinal walls. The tamarind seed powder actually worked better than inulin, a commonly used prebiotic, particularly at higher concentrations.

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The Impact of Psilocybin on High Glucose/Lipid-Induced Changes in INS-1 Cell Viability and Dedifferentiation

Researchers tested whether psilocybin, a compound from magic mushrooms, could protect pancreatic β-cells (which produce insulin) from damage caused by high glucose and fat levels. Using laboratory cells, they found that psilocybin reduced β-cell death by preventing apoptosis and showed promise in reducing dedifferentiation (when cells lose their specialized functions). However, psilocybin didn’t restore the cells’ ability to respond to glucose by releasing insulin.

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Attributes of Culture Bacteria as Influenced by Ingredients That Help Treat Leaky Gut

Researchers tested whether eight natural ingredients commonly used to treat leaky gut would affect the beneficial bacteria used to make yogurt. They found that ingredients like marshmallow root, licorice root, and slippery elm bark not only didn’t harm the yogurt bacteria but actually made them more resistant to stomach acid and bile. This means these ingredients could be safely added to yogurt to boost both the probiotic bacteria and the gut-healing properties of the product.

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Sustainable Innovations in Food Microbiology: Fermentation, Biocontrol, and Functional Foods

This review explores how microorganisms can make food production more sustainable and healthier. It discusses traditional fermented foods like yogurt and sauerkraut, modern biotechnology techniques to reduce food waste and create natural preservatives, and special food ingredients with beneficial bacteria that support digestive and mental health. The paper shows how applying microbial science could help address global food challenges while meeting consumer demands for natural, safe, and healthy products.

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Effects of hallucinogenic drugs on the human heart

Hallucinogenic drugs like LSD and psilocybin affect not only the brain but also the heart. These drugs increase heart rate and contractility mainly through specific serotonin and histamine receptors. While these effects might have therapeutic potential for psychiatric conditions, prolonged use can damage heart valves and cause dangerous arrhythmias. Understanding these cardiac effects is crucial for safe medical use and treatment of overdoses.

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