This study examines cryptococcosis, a fungal infection that affects both animals and humans, across Portugal from 2013-2025. Researchers found that about 4.5% of animal samples tested positive for Cryptococcus species, with infections most common in dogs and cats. The infections peaked during summer months and were most prevalent in central Portugal, with different fungal species affecting different animal types. The research emphasizes the importance of coordinated monitoring across animals, humans, and the environment to better understand and control this disease.