Research Topic: Medical

Heavy Metal-Contaminated Soils and Gastric Cancer Risk: Molecular Insights and the Relevance of a One Health Perspective

Heavy metals like cadmium, arsenic, and lead contaminate agricultural soils and accumulate in crops such as rice and vegetables, which people consume as part of their daily diet. These metals damage stomach cell DNA and trigger inflammation, increasing cancer risk, especially when combined with bacterial infections like H. pylori. A comprehensive approach monitoring soil quality, crop safety, and human health together can help prevent this disease and protect communities from contamination.

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Benefits and risks of hair, skin, and nail supplements in older adults

This article reviews popular supplements that older adults, especially women, take to improve their hair, skin, and nails. While some supplements like nicotinamide show promise for sun-damaged skin, most lack strong evidence of benefit in healthy people. Important risks include biotin interfering with heart and thyroid tests, too much zinc causing copper deficiency, and excess vitamins A and E building up to toxic levels. Doctors should talk to older patients about these supplements and help them make informed decisions based on scientific evidence rather than marketing claims.

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Pathogenic potential of polyextremotolerant fungi in a warming world

Certain fungi can survive extremely harsh conditions like extreme temperatures and dry environments, and many of these same species can cause infections in humans. As the planet warms due to climate change, these fungi are becoming better adapted to higher temperatures, which makes them more dangerous as human pathogens. Scientists are working to better understand these fungi and develop new treatments and vaccines to protect people from fungal infections.

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A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus

A 52-year-old woman with lupus developed a widespread fungal skin infection that was initially mistaken for worsening lupus symptoms. The infection affected her scalp, face, and nails with two different types of fungi. After six months of treatment with antifungal medications, her symptoms resolved completely with no return of the infection during follow-up.

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Wildlife Dermatophytoses in Central Italy (Umbria and Marche Regions): A Fifteen-Year Investigation (2010–2024)

Researchers studied fungal skin infections in wild animals across two Italian regions over 15 years, finding that about 11% carried dermatophyte fungi. Grey squirrels were most commonly infected, and some of these fungi can spread to humans through contact. The study highlights how wild animals act as sentinels for emerging diseases and emphasizes the importance of protective equipment when handling wildlife.

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The Influence of Biogeographic Diversity, Climate and Wildlife on the Incidence of Tick-Borne Encephalitis in Croatia

This study examined tick-borne encephalitis cases in Croatia over 17 years to understand what factors influence disease spread. Researchers found that warmer winters lead to more TBE cases, likely because milder temperatures allow tick populations to survive and thrive better. The disease peaks in summer months when people spend more time outdoors, and certain areas of Croatia have much higher infection rates than others based on their geography and wildlife populations.

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Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa

This study surveyed 131 medical laboratories across 28 African countries to understand what types of infectious disease testing they can perform. Researchers found that while most labs can test for parasites and bacteria, fewer can perform tests for viruses (except HIV) or fungi. The study identified that HIV testing is widely available, but better access to other viral and fungal disease testing is needed to improve healthcare and prepare for future disease outbreaks.

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The impact of climate change on the epidemiology of fungal infections: implications for diagnosis, treatment, and public health strategies

Climate change is making it easier for dangerous fungi to grow and spread to new areas where people have never encountered them before. As temperatures rise and weather becomes more extreme, fungi are becoming resistant to our medicines, especially antifungal drugs used in both farming and hospitals. People living in poverty, displaced by natural disasters, and those without good healthcare access are most vulnerable to these infections. We need to act quickly by developing new treatments, improving diagnosis, reducing agricultural fungicide use, and strengthening healthcare systems in vulnerable communities.

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Fatal Pneumonia Caused by Beauveria bassiana in a Kemp’s Ridley Sea Turtle (Lepidochelys kempii, Garman, 1880) on the Portuguese Coast: Case Report and Review of Beauveria spp. Infections in Reptiles

A young Kemp’s ridley sea turtle, one of the world’s most endangered turtle species, was found off the coast of Portugal and brought to a rehabilitation center. Despite intensive care, the turtle died after 11 days due to a severe fungal lung infection caused by Beauveria bassiana, a fungus that normally infects insects. This case highlights how endangered animals in poor health are vulnerable to opportunistic infections and emphasizes the importance of including fungal disease screening in wildlife rehabilitation programs.

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A case of Blastomyces helicus pneumonia in a dog from a non-endemic region: diagnostic challenges and successful treatment outcome

A dog from Colorado developed a severe respiratory infection that was initially mistaken for a bacterial pneumonia. After antibiotics failed to help, advanced testing revealed the dog had a fungal infection caused by Blastomyces helicus, a rare fungus found in western North America. The dog was successfully treated with an antifungal medication called itraconazole and made a complete recovery within six months, demonstrating the importance of considering fungal infections when standard treatments fail.

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