Research Topic: Invasive candidiasis

Virulence factors of Candida spp. isolated from COVID-19 patients: hydrolytic enzyme activity and biofilm formation

mycolabadmin

During the COVID-19 pandemic, many hospitalized patients developed fungal infections caused by Candida yeasts alongside their coronavirus infection. Researchers studied 71 Candida samples from COVID-19 patients to understand how these fungi cause disease by examining three damaging enzymes they produce and their ability to form protective biofilm layers. The findings showed that these fungi are highly virulent, producing strong enzyme activity that helps them invade tissues and resist treatment, which helps explain why these infections are particularly dangerous in COVID-19 patients.

Read More »

Efficacy and safety of isavuconazole for invasive fungal infections: A systematic review and meta-analysis of randomized controlled trials

mycolabadmin

Isavuconazole is an antifungal medication used to treat serious fungal infections in people with weakened immune systems. This study reviewed and analyzed three clinical trials to compare how well isavuconazole works compared to other antifungal drugs. The results showed that isavuconazole is just as effective as other antifungals but has fewer side effects, particularly fewer problems with liver health and drug-related adverse events. This makes isavuconazole a good alternative choice for patients who cannot use other antifungal medications or who are at risk of liver damage.

Read More »

Efficacy and safety of isavuconazole for invasive fungal infections: A systematic review and meta-analysis of randomized controlled trials

mycolabadmin

Isavuconazole is an antifungal medication used to treat serious fungal infections that can occur in people with weakened immune systems. This research review looked at three clinical trials comparing isavuconazole to other antifungal drugs and found it works just as well while being easier on the liver. Notably, isavuconazole caused fewer drug-related side effects and liver problems compared to voriconazole, another common antifungal drug.

Read More »

Invasive Candidiasis in Contexts of Armed Conflict, High Violence, and Forced Displacement in Latin America and the Caribbean (2005–2025)

mycolabadmin

This comprehensive review examines candida fungal infections in conflict-affected areas of Latin America and the Caribbean, where wars, violence, and displacement create dangerous conditions that make infections more likely and harder to treat. In these regions, mortality from candida bloodstream infections reaches 65% or higher among displaced populations, compared to about 45-60% in regular hospitals. The main problems are lack of proper diagnostic equipment, limited access to effective antifungal medications, malnutrition, overcrowding in shelters, and the emergence of drug-resistant fungal strains.

Read More »
Scroll to Top