immunomodulation – Page 7

The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro

mycolabadmin

Turkey tail mushrooms, used in traditional Chinese medicine for thousands of years, show promise in fighting melanoma skin cancer. Scientists tested mushroom extracts on melanoma cells in the laboratory and found they kill cancer cells through multiple mechanisms, including triggering programmed cell death and activating the immune system. The mushroom extract also reduced cancer cell migration and showed potential to work better when combined with standard chemotherapy drugs like paclitaxel. These findings suggest turkey tail could be a valuable addition to melanoma treatment strategies.

Nuts, vegetables, fruits, and protein dietary pattern during pregnancy is inversely associated with risk of childhood allergies: a case–control study

mycolabadmin

This study found that pregnant women who ate more nuts, vegetables, fruits, and protein had children with significantly lower rates of allergies. The research compared the diets of mothers whose children developed allergies to mothers of allergy-free children and discovered that higher consumption of omega-3 fatty acids and folic acid during pregnancy was linked to healthier immune development. The findings suggest that eating a nutrient-rich diet during pregnancy may help protect babies from developing allergies and other immune-related conditions.

Recent Discoveries on Marine Organism Immunomodulatory Activities

mycolabadmin

Scientists are discovering that creatures from the ocean produce powerful substances that can help our immune system fight diseases like cancer and inflammation. These marine organisms—from tiny algae to sponges to fish—create natural compounds that can either boost or calm down our immune response depending on what we need. Several of these ocean-derived medicines are already approved for treating serious diseases, and many more are being tested in clinical trials. The ocean covers 70% of our planet and most of it remains unexplored, suggesting there are many more beneficial compounds waiting to be discovered.

The Genus Cordyceps Sensu Lato: Their Chemical Constituents, Biological Activities, and Therapeutic Effects on Air Pollutants Related to Lung and Vascular Diseases

mycolabadmin

Cordyceps mushrooms have been used in traditional Chinese medicine for centuries and are now being studied scientifically for their potential health benefits. These mushrooms contain powerful compounds that may help protect our lungs from air pollution effects and support heart health. Recent clinical studies show promising results for treating conditions like COPD, asthma, and even improving athletic performance in healthy people.

Edible Mushrooms and Beta-Glucans: Impact on Human Health

mycolabadmin

Mushrooms contain compounds called β-glucans that can help boost your immune system and reduce inflammation. These compounds show promise in cancer treatment when combined with conventional therapies and may help fight infections. While mushrooms have long been used in traditional medicine, modern research is confirming their health benefits and understanding how they work in the body.

Clinical benefits of β-glucan supplementation in children: a review

mycolabadmin

This review examines how β-glucan, a natural fiber found in mushrooms, yeast, and grains, can help strengthen children’s immune systems and improve their health. Studies show that β-glucan supplementation may reduce the frequency and severity of colds and respiratory infections, improve digestive health, help control blood sugar levels, and support overall development. The evidence suggests that β-glucan could be a valuable dietary supplement for malnourished or immunocompromised children worldwide.

Armillaria mellea Mycelia Alleviate PM2.5-Induced Pulmonary Inflammation in Murine Models

mycolabadmin

This study found that Armillaria mellea mushroom mycelia can help protect lungs from damage caused by PM2.5 air pollution. When tested in both laboratory cells and mice, the mushroom extract reduced inflammatory responses and restored healthy lung function. The protective effects work by reducing harmful inflammatory molecules and blocking inflammatory signaling pathways. These findings suggest A. mellea could be developed into a natural supplement to help protect respiratory health in areas with poor air quality.

Modulating effects of Phellinus linteus polysaccharides on antioxidant capacity, immune function, intestinal function and microbiota in lipopolysaccharide-challenged broilers

mycolabadmin

Researchers studied how a medicinal mushroom extract called Phellinus linteus polysaccharides could help broiler chickens recover from immune stress caused by bacterial toxins. The supplement improved the chickens’ growth, reduced harmful inflammatory responses, and promoted beneficial gut bacteria while reducing harmful ones. The treatment strengthened the intestinal barrier and restored the chickens’ natural antioxidant defenses. This suggests the mushroom supplement could be a natural alternative to antibiotics for improving poultry health on farms.

Three-phase extraction of polysaccharide from Stropharia rugosoannulata: Process optimization, structural characterization and bioactivities

mycolabadmin

Researchers developed an efficient new method called three-phase extraction to isolate beneficial compounds called polysaccharides from wine cap mushrooms (Stropharia rugosoannulata). These polysaccharides showed strong antioxidant properties and boosted immune cell activity in laboratory tests by triggering specific cellular pathways. The findings suggest these mushroom extracts could become useful ingredients in functional foods or medicines to support immune health.

Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

mycolabadmin

Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

Research Topic: immunomodulation