immunomodulation – Page 3

Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity

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This study investigated fermenting water chestnut shells with a medicinal mushroom called Ganoderma sinense to create a more potent health product. Under optimal fermentation conditions, the resulting material showed significantly improved immune-boosting and antioxidant properties when tested in laboratory cells. The fermentation process changed the structure of polysaccharides and increased beneficial compounds, potentially transforming agricultural waste into a valuable functional food or supplement.

Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production—A Review

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Medicinal mushrooms like Reishi, Lion’s Mane, and Shiitake contain powerful compounds that may help fight cancer, boost immunity, and reduce inflammation. These mushrooms are low in calories and can be added to everyday foods like bread, pasta, and meat products to boost their nutritional value. While promising, more research is needed to confirm how much people should consume and whether they interact safely with medications.

The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy

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Oyster mushrooms contain special compounds that may help fight cancer and boost the immune system. These mushrooms have antioxidants and other natural chemicals that can slow cancer cell growth and trigger cancer cells to die. When combined with standard cancer treatments, oyster mushroom supplements might improve quality of life and reduce side effects. More research is needed, but oyster mushrooms show promise as an affordable, natural addition to cancer treatment plans.

Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts

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This study examined four types of edible mushrooms to see if they could protect against aging and fight harmful bacteria. Researchers gave mice an aging-inducing substance and then treated them with mushroom extracts. The mushrooms, particularly Lion’s Mane (Hericium erinaceus), helped prevent brain and liver damage, reduced inflammation, and showed antibacterial effects against multiple bacterial strains. These findings suggest mushrooms could be useful natural supplements to promote health and combat age-related decline.

A brief overview of the medicinal and nutraceutical importance of Inonotus obliquus (chaga) mushrooms

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Chaga mushrooms are a traditional medicine used for centuries in Eastern Europe and Asia that contains powerful compounds beneficial for health. These mushrooms have been shown to help fight cancer, reduce inflammation, boost immunity, and protect cells from damage through their natural antioxidants. Modern scientific research is confirming what traditional healers have known for centuries about this remarkable fungus, making it an increasingly popular natural supplement for health and wellness.

Extraction, Characterization, Biological Properties, and X-Ray Fluorescence Analysis of Functional Polysaccharides Derived from Limnospira platensis

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Spirulina (Limnospira platensis) is a nutrient-dense microalga that contains beneficial polysaccharides with multiple health benefits. Researchers extracted and analyzed these polysaccharides, finding they have strong antioxidant properties and can help regulate blood sugar levels by inhibiting α-glucosidase enzymes. These compounds also support beneficial gut bacteria growth, making spirulina a promising natural ingredient for functional foods and health supplements.

Lentinan Alleviated PM2.5 Exposure-Induced Epithelial–Mesenchymal Transition in Pulmonary Epithelial Cells by Inhibiting the GARP/TGF-β/Smad Pathway

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Air pollution particles (PM2.5) can cause serious lung damage by triggering a process called epithelial-mesenchymal transition, where lung cells lose their protective qualities. This study found that a natural compound called lentinan, derived from shiitake mushrooms, can help prevent this harmful process by blocking a protein called GARP. The research suggests that lentinan could be a promising natural treatment for lung diseases caused by air pollution.

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo

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Researchers tested a mushroom extract from Cordyceps militaris to see if it could protect mice from lung injury caused by bacterial toxins. The extract successfully reduced inflammation, prevented excessive mucus production, and decreased immune cell buildup in the lungs. These findings suggest that this mushroom extract could potentially be used as a natural supplement to help prevent respiratory diseases and support lung health.

Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

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Mushrooms are nutritional powerhouses containing as much high-quality protein as meat and soybeans, with complete amino acid profiles needed for human health. Beyond basic nutrition, mushroom proteins possess remarkable healing properties including anti-cancer, immune-boosting, and blood pressure-lowering effects. These sustainable proteins are increasingly used in food fortification, sports supplements, and therapeutic medicines. Growing mushrooms as mycelium or using novel cultivation methods makes protein production faster, more efficient, and environmentally friendly.

Nature’s Own Pharmacy: Mushroom-Based Chemical Scaffolds and Their Therapeutic Implications

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This comprehensive review explores how mushrooms can be used as natural medicines. Various mushroom species contain powerful compounds that can fight cancer, boost immunity, reduce inflammation, and treat infections. The paper details 15 important medicinal mushrooms and their therapeutic uses, showing that mushrooms are indeed a nature’s pharmacy with significant potential for treating many diseases.

Research Topic: immunomodulation