Research Topic: immune priming

Decursin, Identified via High-Throughput Chemical Screening, Enhances Plant Disease Resistance via Two Independent Mechanisms

Researchers identified a natural compound called decursin from angelica plants that helps plants fight off dangerous fungal infections in two ways: it strengthens the plant’s own immune system and directly kills the fungal pathogens. This dual-action approach makes decursin a promising natural alternative to synthetic fungicides for protecting crops like wheat and tomatoes from diseases. The compound shows particular promise because it comes from plants, breaks down easily in the environment, and is more effective than other natural antimicrobial compounds currently used in agriculture.

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A root-based N-hydroxypipecolic acid standby circuit to direct immunity and growth of Arabidopsis shoots

Plants communicate with their shoots through chemical signals produced in their roots when soil microorganisms are present. Researchers discovered that a molecule called N-hydroxypipecolic acid acts like an on-off switch controlled by two proteins, FMO1 and UGT76B1. Beneficial fungi suppress the ‘off’ switch, allowing this signal to travel to leaves where it boosts immunity against disease. Different amounts of this signal have different effects: small amounts help the plant grow, while large amounts strengthen defenses but slow growth.

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