Research Topic: hospital-acquired infections

Prevalence and antifungal susceptibility profiles of Candida isolates among patients with candiduria: a multiplex PCR assay

Researchers studied urinary tract infections caused by yeast (Candida species) in hospitalized patients. Using advanced molecular testing, they found that while the common yeast Candida albicans was most prevalent, other yeast species were increasingly showing resistance to antifungal medications, particularly to fluconazole. The study highlights the importance of identifying which specific yeast species is causing an infection to choose the most effective treatment.

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Prevalence and antifungal susceptibility profiles of Candida isolates among patients with candiduria: a multiplex PCR assay

This study examined Candida yeast infections in urine samples from hospitalized patients in Iran. Researchers identified seven different Candida species using a specialized PCR test and tested how well they responded to three antifungal medications. They found that while Candida albicans was most common, other species showed much higher resistance to fluconazole treatment. The findings highlight the importance of proper species identification for choosing the right treatment.

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Genetic sequencing of the airborne fungal spectrum and air quality at a public hospital in Mexico City

Researchers tested the air inside and outside a Mexico City hospital to identify harmful fungi that could make patients sick. Using two different sampling methods, they found 27 different fungal species, including dangerous ones like Aspergillus fumigatus that cause serious infections especially in people with weakened immune systems. The study shows that hospitals need better air monitoring systems to protect vulnerable patients from these airborne infections.

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Influenza-related invasive pulmonary aspergillosis in an infectious disease ward at a pulmonary referral center in Iran

This study examined patients hospitalized with influenza who developed a serious fungal infection caused by Aspergillus fungus. Among 109 influenza patients, about 9% developed this fungal complication which significantly increased their risk of death and required longer hospital stays. Patients with existing lung diseases were at higher risk, and those with the fungal infection also had more bacterial superinfections. The findings highlight the importance of recognizing and treating this serious fungal complication in hospitalized influenza patients.

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Epidemiology of Candidemia, Candiduria and Emerging Candidozyma (Candida) auris Across Gulf Cooperative Council Countries and Yemen in the Arabian Peninsula

This comprehensive review examines fungal bloodstream and urinary tract infections caused by Candida species across Middle Eastern countries. The study shows that while Candida albicans remains common, dangerous antibiotic-resistant strains like Candidozyma auris are increasingly appearing in hospitals. The research highlights that better diagnostic tools and infection prevention practices are urgently needed in the region to protect patients and reduce deaths from these serious infections.

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Prevalence of fungi and their antifungal and disinfectant resistance in hospital environments: insights into combating nosocomial mycoses

This study examined how fungal infections spread in hospital settings by testing air and surfaces in Iranian hospital intensive care units. Researchers found that dangerous fungi like Aspergillus and Rhizopus were commonly present, especially in air ducts, and many of these fungi could resist common antifungal medications and disinfectants. The findings suggest that hospital environments serve as sources of infection for vulnerable patients and that better cleaning and air filtration systems are needed to protect hospitalized patients.

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Nosocomial Diarrhea Distribution by Cryptosporidium in Isfahan

Researchers tested 217 patients who developed diarrhea in a hospital in Isfahan, Iran to see if a parasite called Cryptosporidium was responsible. Using advanced DNA testing, they found the parasite in only 2 out of 217 patients (less than 1%). This suggests that while this parasite can spread in hospitals, it is not a major cause of diarrhea in this particular hospital, which likely has good hygiene practices.

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