Research Topic: herbal medicine

Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

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The safety and efficacy of Houtou Jianweiling tablet in patients with chronic non-atrophic gastritis: a double-blind, non-inferiority, randomized controlled trial

This study tested a traditional Chinese herbal medicine called Houtou Jianweiling Tablet against omeprazole, a common stomach medication, for treating chronic stomach inflammation. The herbal tablet worked just as well as the conventional drug at relieving stomach pain, bloating, and reducing harmful bacteria, while being very safe with almost no side effects. This suggests that people with mild to moderate stomach inflammation could use this natural herbal alternative instead of, or alongside, conventional medications.

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Traditional Chinese Medicine for Hashimoto’s Thyroiditis: Focus on Selenium and Antioxidant Phytochemicals

Hashimoto’s thyroiditis is a common autoimmune thyroid disease that often leads to symptoms like fatigue and reduced quality of life. While standard treatment uses thyroid hormone replacement, it doesn’t address the underlying inflammation and oxidative stress. This review explores how traditional Chinese medicine approaches, often combined with selenium, may help reduce thyroid antibodies and improve symptoms through their antioxidant and anti-inflammatory properties.

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Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

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The Therapeutic Effect and Mechanism of Traditional Chinese Medicine in Type 2 Diabetes Mellitus and Its Complications

Traditional Chinese Medicine uses various herbs and plant compounds to treat Type 2 diabetes by improving how the body controls blood sugar and protects the pancreas. Many common TCM herbs like ginseng, rehmannia, and coptis work through natural mechanisms that reduce inflammation, protect cells from damage, and improve how the body uses insulin. Research shows TCM may also help prevent or reduce diabetes-related complications affecting the eyes, kidneys, and nerves. These herbal treatments offer potential benefits with fewer side effects compared to conventional medications.

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A Systematic Review on Important Risk Factors and Possible Involved Mechanisms of Medicinal Plants on Nonalcoholic Fatty Liver Disease

This comprehensive review examined 43 medicinal plants that can help prevent and treat fatty liver disease (NAFLD), which is increasingly common in developed countries. Most of these plants work by reducing cholesterol and triglycerides, helping with weight management, improving blood sugar control, and lowering blood pressure. The plants contain natural compounds like flavonoids and polyphenols that reduce inflammation and oxidative stress in the liver. Using these herbal supplements alongside other lifestyle changes may offer a promising natural approach to managing NAFLD and its related conditions.

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Evaluation of the Cytotoxicity and Antifungal Efficacy of Crocus sativus (saffron) Petals on Clinical Isolates of Candida albicans

Researchers tested saffron petals as a natural antifungal treatment against Candida albicans, a common fungal infection. While the saffron extract was less potent than the standard drug fluconazole, it showed promise as a safer alternative with minimal toxicity to human cells. The findings suggest saffron petals could be a cost-effective herbal option for treating fungal infections, especially as resistance to conventional antifungals increases.

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Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms

This review examines how medicinal plants can help manage nausea and vomiting caused by cancer chemotherapy. Over 22 plants including ginger, cannabis, mint, and turmeric work through multiple mechanisms like blocking serotonin pathways and reducing inflammation. Beyond reducing symptoms, these plants may also enhance chemotherapy effectiveness and boost immune function. The research suggests combining medicinal plants with standard cancer treatments could improve patient outcomes and quality of life.

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Potential of Indonesian Herbal as an Anti-Cancer Therapy: A Systemic Review of in vitro Studies

This review examined eight Indonesian herbal plants that show promise in laboratory studies for fighting various types of cancer. Soursop leaves were the most researched and consistently showed the ability to kill or slow cancer cells in test tubes by triggering natural cell death pathways. The herbs work through bioactive compounds like flavonoids and alkaloids that can interfere with how cancer cells divide and survive. While these results are encouraging, more research is needed to confirm effectiveness in humans.

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Antifungal efficacy of caffeic acid and nano-caffeic acid particles against candidiasis: an in vitro study

Researchers developed a nano-particle form of caffeic acid, a natural compound found in coffee and tea, to treat oral yeast infections (candidiasis). The nano-version showed better antifungal activity than regular caffeic acid, though not as strong as prescription antifungal drugs. Since it comes from plants with fewer side effects, it could offer an alternative treatment option for patients with candidiasis.

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