Research Topic: gut microbiota

In vitro fermentation characteristics and prebiotic activity of herbal polysaccharides: a review

This review explores how plant-based polysaccharides from traditional herbs can benefit our health by feeding good bacteria in our gut. When these polysaccharides are fermented by our gut microbiota, they break down into smaller compounds that produce short-chain fatty acids, which have anti-inflammatory and immune-boosting effects. The research shows that different herbs have different structures that are recognized by specific beneficial bacteria, which suggests we can develop personalized functional foods tailored to promote specific health benefits.

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Insights into the Mechanisms and Functional Effects of Insoluble Dietary Fiber Modification: A Review

Insoluble dietary fiber is important for digestive health but its rigid structure limits its usefulness in processed foods and medicine. Scientists can modify this fiber using various techniques like heating, pressure, enzymes, and chemicals to make it more effective. When combined properly, these modification strategies can dramatically improve dietary fiber’s ability to lower cholesterol, control blood sugar, and promote beneficial gut bacteria, making it valuable for functional foods and health applications.

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The Active Components of Traditional Chinese Medicines Regulate the Multi-Target Signaling Pathways of Metabolic Dysfunction-Associated Fatty Liver Disease

This comprehensive review examines how traditional Chinese medicine ingredients can treat fatty liver disease through multiple biological pathways simultaneously. Unlike conventional drugs that target a single pathway, TCM compounds address the complex, interconnected causes of the disease including fat accumulation, inflammation, and tissue damage. The research identifies dozens of effective herbal compounds and proposes a new framework for designing TCM treatments tailored to individual patient needs.

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Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration

This study tested whether common and medicinal mushrooms could protect against Alzheimer’s disease by reducing harmful reactive oxygen species in brain cells. Researchers tested three mushroom types using digestive simulation to see what the body could absorb, plus key compounds made by gut bacteria. The mushroom extracts and certain bacterial metabolites successfully reduced cellular damage markers and improved behavior in disease-model worms, suggesting mushroom-rich diets may help prevent neurodegeneration.

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Sustainable Innovations in Food Microbiology: Fermentation, Biocontrol, and Functional Foods

This review explores how microorganisms can make food production more sustainable and healthier. It discusses traditional fermented foods like yogurt and sauerkraut, modern biotechnology techniques to reduce food waste and create natural preservatives, and special food ingredients with beneficial bacteria that support digestive and mental health. The paper shows how applying microbial science could help address global food challenges while meeting consumer demands for natural, safe, and healthy products.

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Comparative Analysis of Freeze-Dried Pleurotus ostreatus Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds

Researchers studied oyster mushrooms processed in different ways to understand their health benefits. The study found that cooked oyster mushroom powders can kill harmful bacteria and promote the growth of beneficial gut bacteria. These mushrooms also contain special particles called carbon nanodots that form during cooking and may enhance their health-promoting effects. The findings suggest oyster mushrooms could help maintain a healthy gut microbiota naturally.

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From Microbes to Myocardium: A Comprehensive Review of the Impact of the Gut-Brain Axis on Cardiovascular Disease

Your gut bacteria play a surprising role in heart health through a communication network called the gut-brain axis. When the balance of gut bacteria is disrupted (dysbiosis), it can lead to heart disease, high blood pressure, and clogged arteries. Beneficial bacteria produce helpful compounds like short-chain fatty acids that reduce inflammation and protect blood vessels, while harmful bacteria produce compounds that increase heart disease risk. Simple interventions like eating more fiber, taking probiotics, managing stress, and exercising can help maintain a healthy gut microbiome and improve heart health.

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Synbiotic microencapsulation of Lactiplantibacillus plantarum-lentinan for enhanced growth in broilers

Researchers developed a special protective coating for beneficial bacteria called L. plantarum mixed with lentinan from mushrooms. This mixture helps chickens grow better and stay healthier by improving their digestion and fighting harmful bacteria. When the coated bacteria reach the chicken’s intestines, they release their beneficial properties, improving growth rate and immune function without using antibiotics.

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Gut microbiota-mediated regulation of lipid metabolism by single herbal medicines: a review focused on cold/hot properties

This review examines how traditional Chinese herbal medicines can help regulate lipid metabolism and lower cholesterol by changing the composition of bacteria in our gut. Different herbs have different properties – some are considered cooling and others warming – and these properties affect which gut bacteria they increase or decrease. The review found that herbal medicines work best when matched to a person’s body constitution, and provides a framework for choosing the right herb based on whether someone has a heat-type or cold-type condition.

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Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

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