Research Topic: gut microbiota

Efficacy of prebiotic, probiotic and synbiotic administration in improving growth in children aged 0–59 months living in low- and middle-income countries: a systematic review and meta-analysis

This comprehensive review examined whether giving children special dietary supplements containing beneficial bacteria and their food sources (prebiotics, probiotics, or synbiotics) helps them grow better in low-income countries. The analysis of eight studies found that these supplements may help children gain weight, especially those who are malnourished, though the evidence remains limited. More research is needed to fully understand whether these supplements are truly effective for promoting healthy growth in young children.

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Effects of fiber sources with different solubilities on the growth performance, nutrient metabolism, antioxidant, immune capacity and intestinal health of meat geese

This study examined how different types of dietary fiber affect the health and growth of meat geese. Researchers compared three fiber sources with different levels of solubility: wheat bran (highly soluble), alfalfa meal (moderately soluble), and bamboo meal (low solubility). They found that the highly soluble fiber source improved growth, enhanced immune and antioxidant functions in the intestines, and promoted beneficial bacteria, making it the best choice for geese farming.

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Sex-Specific Associations Between Prebiotic Supplement Intake and Sarcopenia Risk: Evidence From NHANES

This study examined whether taking prebiotic supplements helps prevent sarcopenia (age-related muscle loss) differently in men versus women using health data from thousands of Americans. Researchers found that women who consumed prebiotics had significantly lower rates of sarcopenia, while this benefit was not observed in men. These findings suggest that prebiotic supplements may be particularly beneficial for women’s muscle health, though more research is needed to understand why this sex difference exists.

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Interventions targeting the gut-liver axis: A potential treatment strategy for metabolic dysfunction-associated steatotic liver disease

Your gut bacteria play a crucial role in liver health. When harmful bacteria build up in your gut, they can trigger liver inflammation and fat accumulation, leading to fatty liver disease. Researchers found that simple lifestyle changes like intermittent fasting, eating certain foods that feed good bacteria, and maintaining a healthy diet can restore healthy gut bacteria, strengthen your intestinal barrier, and reduce liver disease. This gut-focused approach could offer new ways to prevent and treat fatty liver disease beyond current treatments.

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Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

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Association of the use of nonfood prebiotics, probiotics, and synbiotics with total and cause-specific mortality: a prospective cohort study

This study of over 53,000 American adults found that people taking nonfood supplements containing prebiotics, probiotics, or synbiotics had significantly lower risks of dying from any cause, heart disease, cancer, or other causes compared to those who didn’t take these supplements. The benefits were particularly strong in women and people without high blood pressure. These findings suggest that these supplement types may play an important role in preventing early death.

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Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice

Researchers tested a supplement called Slim containing natural compounds like berberine, coenzyme Q10, and beet pulp on obese mice. After 4 weeks, the supplement improved cholesterol and triglyceride levels, increased beneficial gut bacteria, and strengthened the intestinal barrier. The results suggest this combination of natural ingredients works together synergistically to improve gut health and metabolic function in obesity.

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Winning the battle of intestinal peace with Bacillus—a multifaceted approach to animal health, immunity, and future applications in monogastric livestock production

This review examines how Bacillus bacteria, when added to animal feed, can improve the health and growth of chickens and pigs. These bacteria work by producing beneficial compounds that strengthen the gut, improve digestion, reduce harmful bacteria, and boost the immune system. Bacillus probiotics offer a natural alternative to antibiotics, helping reduce antibiotic resistance while keeping animals healthier and more productive.

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Nanoencapsulation of Biotics: Feasibility to Enhance Stability and Delivery for Improved Gut Health

This review explores how tiny nanoparticles can protect beneficial bacteria and dietary compounds as they travel through the digestive system. These nanotechnologies help probiotics survive stomach acid and reach the intestines where they provide health benefits. The research shows promising results for treating digestive diseases and improving overall gut health through better delivery of microbiota-modulating substances.

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Enrichment of Artemia With Synbiotic and Its Effects on Growth Nutrient Utilization Survival and Gut Microbial Communities of Larval Hybrid Catfish (Clarias microstomus × Clarias gariepinus)

This study shows that enriching brine shrimp (Artemia) with beneficial bacteria and prebiotic fiber significantly improves growth and health in young catfish. The enriched shrimp were fed to catfish larvae for two weeks, resulting in better weight gain, faster growth rates, and more efficient feed conversion. The beneficial bacteria successfully colonized the fish’s gut and promoted a healthier microbiota, offering an environmentally friendly alternative to antibiotics in fish farming.

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