Fungal infections – Page 13

Disseminated mucormycosis leading to a fatal gastrointestinal perforation in a pediatric case of EBV-associated Hemophagocytic lymphohistiocytosis

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A 12-month-old girl developed a serious immune system disorder called hemophagocytic lymphohistiocytosis triggered by Epstein-Barr virus infection. Despite aggressive treatment, she developed a life-threatening fungal infection caused by mucormycosis that spread throughout her digestive system. The case illustrates how fungal infections can rapidly progress and become fatal in children with severely weakened immune systems, emphasizing the need for doctors to recognize early warning signs like tissue darkening on the skin.

Acute fungal endometritis in women with abnormal uterine bleeding: Clinical and microbiological insights

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Women with persistent abnormal uterine bleeding often undergo extensive testing without finding a cause. This study discovered that fungal infections, caused by Candida species, may be responsible for about 12% of such cases. The researchers found that direct sampling of the uterine lining is essential for diagnosis since surface vaginal cultures miss these infections. Treatment with an antifungal medication called voriconazole combined with surgical cleaning of the uterus proved effective in resolving the condition.

Tinea genitalis profunda caused by Microsporum canis: A case report and literature review

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A 23-year-old woman developed a severe fungal infection in her genital area caused by a fungus typically found in dogs. The infection initially appeared bacterial and did not respond to antibiotics. Fungal cultures identified Microsporum canis, which was successfully treated with oral antifungal medications, though the patient experienced some scarring and pigmentation changes.

Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

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This case study describes three patients with diabetes who developed a serious lung infection caused by a rare fungus called mucormycosis. The infection presented with various symptoms like cough, fever, and weight loss, and was diagnosed using lung tissue samples that showed the characteristic fungal structures. Two patients recovered with prolonged antifungal medication treatment, while one patient unfortunately died despite receiving prompt treatment, highlighting how serious this infection can be.

Invasive nasal and paranasal mucormycosis in a patient with severe dengue fever and multiple risk factors: A case report and literature review

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A 50-year-old woman in Vietnam developed a rare and deadly fungal infection called mucormycosis while recovering from dengue fever. She had weakened immunity from taking steroids for other conditions and from the dengue virus itself. The infection caused black, dead tissue to rapidly spread in her nose and around her eye. Despite treatment with antifungal medications, the infection progressed, and she died within days. The case shows how important it is to watch for dangerous opportunistic infections in dengue patients, especially those already dealing with weakened immune systems.

A case report of childhood onychomycosis caused by the rare yeast Kodamaea ohmeri

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A 5-year-old girl in Vietnam developed a nail infection caused by a rare yeast called Kodamaea ohmeri, which typically affects adults with diabetes or weak immune systems. The infection, appearing as white discoloration on the nails, was successfully treated with a topical antifungal cream applied three times daily for one month. This is the first reported case of this rare yeast causing nail infection in a child in Vietnam, and it demonstrates that topical treatment can be effective for fungal nail infections in children whose nails are thinner than adults.

A Pragmatic Strategy for Improving Diagnosis of Invasive Candidiasis in UK and Ireland ICUs

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Diagnosing invasive candidiasis (a serious fungal infection in ICU patients) is challenging because current blood culture tests are slow and insensitive. This paper presents a practical five-step diagnostic guide for UK and Ireland hospitals that combines risk assessment, biomarker tests, and rapid identification methods to diagnose the infection faster and more accurately. Using this strategy helps doctors avoid unnecessary antifungal drugs while ensuring seriously ill patients receive appropriate treatment quickly, ultimately improving survival rates.

Diagnostic Capacity for Fungal Infections in Tertiary Hospitals in Nigeria and Ghana – An Onsite Baseline Audit of 9 Sites

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Researchers audited nine hospital laboratories in Nigeria and Ghana to assess their ability to diagnose fungal infections. They found that most laboratories lack basic equipment like microscopes and trained staff for fungal testing. The study revealed critical gaps in infrastructure and resources needed to identify serious fungal diseases, highlighting the need for investment in laboratory capacity building in African healthcare systems.

Rasamsonia argillacea brain abscess in a lung transplant recipient: an unexpected infection by an unusual fungal pathogen

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A 65-year-old woman who received a lung transplant developed a rare and serious brain infection caused by an unusual fungus called Rasamsonia argillacea. The infection was difficult to diagnose because it looks similar to more common molds under the microscope. During the investigation of this unexpected infection, doctors discovered that the patient had a rare genetic disorder affecting her immune system that had never been diagnosed. This case highlights how unusual infections can reveal hidden immune system problems.

Masquerading Yeast: A Case Report of Lomentospora prolificans Fungemia With a Diagnostic Twist

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This case describes a patient with blood cancer who developed a rare and deadly mold infection called Lomentospora prolificans while receiving cancer treatment. The infection was difficult to diagnose initially because the fungal structures looked similar to yeast under the microscope, and a molecular test gave a false positive result for a different fungus. Unfortunately, the infection was resistant to all available antifungal medications and the patient died.

Research Topic: Fungal infections