Research Topic: fungal-host interactions

Unveiling the hidden arsenal: exploring secondary metabolites and fungal development in pathogenic fungi

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Dangerous fungi produce hidden chemical compounds that help them infect humans and crops while also potentially serving as medicines. Scientists are studying how these compounds work and how fungi make them to develop better treatments and protect our food supply. This editorial highlights recent research showing that understanding fungal chemistry from genetic, ecological, and medical perspectives will help us fight fungal diseases as resistance increases.

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The Egh16-like virulence factor TrsA of the nematode-trapping fungus Arthrobotrys flagrans facilitates intrusion into its host Caenorhabditis elegans

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Researchers discovered how a soil fungus that traps worms produces a special protein called TrsA to break down the worm’s protective outer layer. This protein acts like molecular scissors that weakens the worm’s skin and helps the fungus invade and spread throughout the worm’s body. The findings reveal a clever infection strategy used by predatory fungi and could help understand how similar fungi attack other organisms.

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