Research Topic: fungal genome assembly

Gapless near Telomer-to-Telomer Assembly of Neurospora intermedia, Aspergillus oryzae, and Trichoderma asperellum from Nanopore Simplex Reads

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Scientists developed an automated computer workflow that can assemble complete fungal genomes using data from a single type of DNA sequencer. They tested this method on three industrially important fungi and successfully created high-quality, gap-free genome maps for all three. This breakthrough means researchers can now generate high-quality fungal genome sequences faster and more cheaply than before, which will help improve our understanding of these organisms.

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Whole-genome sequencing of Fusarium oxysporum K326-S isolated from tobacco

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Scientists have sequenced the complete genetic code of a fungus called Fusarium oxysporum that infects tobacco plant roots, causing them to wilt and turn brown. This fungus is a major problem for tobacco farmers because it lives in soil and is difficult to control. By mapping out all 17,272 genes in this fungus, researchers now have detailed information that will help them develop better ways to prevent and manage this disease.

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Gapless near Telomer-to-Telomer Assembly of Neurospora intermedia, Aspergillus oryzae, and Trichoderma asperellum from Nanopore Simplex Reads

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Researchers developed a new method to create complete, high-quality genetic maps of fungi using a single affordable sequencing technology from Oxford Nanopore. They created an automated computer program that processes the sequencing data without human intervention and successfully assembled complete genomes for three industrially important fungal species. This breakthrough could make it much easier and cheaper for scientists to study and use fungi for producing medicines, food ingredients, and other useful compounds.

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