Research Topic: epidemiology

A prospective, multicenter study of invasive fungal disease caused by molds in children and adults in Chile

Researchers in Chile studied serious mold infections in 176 hospitalized patients (adults and children) over two years. They found that aspergillosis (a lung infection caused by Aspergillus mold) was the most common, especially in patients whose immune systems were compromised by cancer, transplants, or medications. Interestingly, nearly 40% of cases also involved COVID-19 infection. Although almost all patients received antifungal medications, survival rates were concerning, with about one-third of patients still alive after six months.

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Epidemiological Profile of Otomycosis at the Peace Hospital of Ziguinchor (Senegal)

This study examined fungal ear infections in a hospital in Senegal and found that about 85% of suspected cases were actually caused by fungi. The most common fungi were Aspergillus and Candida species. The research shows that itching was the main symptom associated with fungal ear infections, and that proper diagnosis is important to avoid unnecessary antibiotic use and provide better treatment.

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Incidence and Risk Factors for Invasive Fungal Infection in Patients with Hematological Malignancies at a Tertiary Hospital in Malaysia

This study examined fungal infections in cancer patients with blood disorders in a Malaysian hospital. Researchers found that about 7.6% of patients developed serious fungal infections, mainly from Candida species. Using antifungal medications to prevent infection significantly reduced the risk, though some patients still developed infections while taking preventive medications. The findings highlight the importance of appropriate antifungal treatment strategies in managing these vulnerable patients.

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Superficial Fungal Infections in the Pediatric Dermatological Population of Northern Poland

This study examined fungal skin infections in children and teenagers in northern Poland from 2019 to 2024. Researchers tested over 1,200 young patients and found that about 1 in 5 had a fungal infection. The most common culprits were specific fungi that cause scalp infections in young children and foot/nail infections in teenagers. Interestingly, children living in rural areas were more likely to have these infections, even though more urban children were tested.

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Changing Climate, Changing Candida: Environmental and Social Pressures on Invasive Candidiasis and Antifungal Resistance in Latin America

Invasive fungal infections caused by Candida species are becoming increasingly common and dangerous in Latin American hospitals, with newer strains showing resistance to multiple antifungal drugs. Rising temperatures from climate change and widespread use of fungicides in agriculture appear to be selecting for these resistant fungi. Most hospitals in the region lack advanced diagnostic tools to quickly identify which fungal strain is causing infection, leading to delayed and sometimes inappropriate treatment. Implementing better diagnostic access, stricter antifungal use policies, and coordinated surveillance programs across the region could help control this growing public health problem.

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A cross-sectional study of the association between plant-based diet indices and kidney stones among Iranian adults

A study of nearly 10,000 Iranian adults found that people who followed a plant-based diet had a higher risk of developing kidney stones. However, the quality of plant-based eating did not matter—neither healthful nor unhealthful plant-based diets changed the risk significantly. This suggests that while plant-based diets are generally healthy, people at risk for kidney stones should ensure adequate calcium intake and proper hydration.

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Prevalence of Tinea pedis in military personnel: a systematic review and meta-analysis

Athlete’s foot is a common fungal infection affecting military personnel at rates around 17% globally. Military environments create perfect conditions for this infection through close living quarters, humidity from sweat and boots, and shared facilities. The study found that regions with hot, humid climates have higher infection rates, and proper diagnosis using both microscopy and culture tests is important for accurate detection. Improved hygiene, better-designed footwear, and access to antifungal treatments can significantly reduce infection rates in military settings.

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Etiological Agents and Predisposing Factors of Superficial Fungal Infections in Northeastern Argentina

Researchers studied fungal skin infections in a community in northeastern Argentina, finding that 37% of patients had these infections. The most common cause was a fungus called Trichophyton tonsurans. Poor living conditions like overcrowding and lack of clean water increased infection risk. The study shows that fungal skin infections are a significant health problem in areas with limited access to basic sanitation and water services.

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Gastrointestinal and Intra-Abdominal Mucormycosis in Non-Haematological Patients—A Comprehensive Review

This review examines a serious but rare fungal infection called mucormycosis that affects the stomach and intestines. The infection most commonly occurs in patients with diabetes, those who have received organ transplants, or those in intensive care units. Diagnosis can be difficult because symptoms are non-specific, but prompt treatment with antifungal medications and surgery when possible significantly improves survival rates. Early recognition and rapid diagnosis are critical for patients to have the best outcomes.

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Recognizing the Importance of Public Health Mycology

This editorial highlights how fungal infections are a growing but overlooked global health crisis, killing about 2.5 million people annually. The paper brings together seven research articles studying different fungal diseases, from lung infections to skin conditions, showing how these diseases spread differently in different populations and how resistance to antifungal medications is increasing. The authors emphasize that better testing, treatment access, and worldwide disease tracking are urgently needed, especially in poorer countries where the burden of fungal disease is highest.

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