Research Topic: enzyme engineering

PRMT5 promotes cellulase production by regulating the expression of cellulase gene eg2 through histone methylation in Ganoderma lucidum

Scientists discovered that a protein called PRMT5 in Ganoderma lucidum mushroom plays a key role in producing cellulase enzymes that break down plant cellulose. By controlling a specific gene (eg2) through a process called histone methylation, PRMT5 increases cellulase production. This finding could help develop more efficient ways to convert agricultural waste like corn straw into useful sugars for biofuels and other industrial products.

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Selective Homologous Expression of Recombinant Manganese Peroxidase Isozyme of Salt-Tolerant White-Rot Fungus Phlebia sp. MG-60, and Its Salt-Tolerance and Thermostability

Scientists studied a special fungus from mangrove forests that can break down tough plant materials in salty environments. They created engineered versions that produce three different types of a cleanup enzyme called manganese peroxidase. One version of this enzyme was found to actually work better in salty conditions and remain stable at high temperatures, making it potentially useful for industrial applications in harsh environments.

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