Research Topic: drug delivery

Antifungal efficacy of caffeic acid and nano-caffeic acid particles against candidiasis: an in vitro study

Researchers developed a nano-particle form of caffeic acid, a natural compound found in coffee and tea, to treat oral yeast infections (candidiasis). The nano-version showed better antifungal activity than regular caffeic acid, though not as strong as prescription antifungal drugs. Since it comes from plants with fewer side effects, it could offer an alternative treatment option for patients with candidiasis.

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Continuous motion of particles attached to cavitation bubbles

Researchers discovered that cavitation bubbles (tiny bubbles created by ultrasound) can push particles through liquid in a controlled manner. The bubbles expand and collapse in a way that creates a net forward push, similar to a pulse engine. This discovery could revolutionize drug delivery by allowing medications to be attached to particles and guided through the body using ultrasound, potentially improving treatments for heart disease and cancer.

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Immunomodulatory natural polysaccharide-based nanoparticles for the treatment of neurodegenerative diseases

Scientists are developing tiny particles made from natural sugar-based compounds that can deliver medicine to the brain while reducing inflammation caused by neurodegenerative diseases like Alzheimer’s and Parkinson’s. These nanoparticles are special because they can cross the protective barrier surrounding the brain and carry therapeutic compounds directly to where they’re needed. The natural polysaccharides used to make these particles have built-in anti-inflammatory properties, making them safer and more effective than traditional approaches. This innovative technology shows promise for treating currently difficult-to-manage brain diseases.

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