Research Topic: drug delivery systems

Strategies and materials for the prevention and treatment of biofilms

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Biofilms are sticky communities of bacteria that form on medical devices and surfaces, making infections very difficult to treat with antibiotics. This review explains how biofilms develop in stages and describes different ways to stop them from forming or to destroy them once they exist. Solutions include special coatings on medical implants, natural plant extracts like essential oils, and engineered proteins called antimicrobial peptides that fight bacteria without creating antibiotic resistance.

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Encapsulation of progesterone in reishi mushroom composite for optimized hormone replacement and targeted anticancer therapy

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Researchers created a new treatment by combining progesterone (a hormone) with reishi mushroom powder to make it work better in the body. The mushroom acts like a protective wrapper that slowly releases the hormone, making it more effective for treating menopausal symptoms and fighting breast cancer cells. The combination also fights harmful bacteria and fungi while remaining stable during storage. This approach combines traditional medicine with modern pharmaceutical science.

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Design and Evaluation of a Inonotus obliquus–AgNP–Maltodextrin Delivery System: Antioxidant, Antimicrobial, Acetylcholinesterase Inhibitory and Cytotoxic Potential

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Researchers studied Chaga mushroom from Romania and developed new ways to package and deliver its beneficial compounds using silver nanoparticles and a food-safe ingredient called maltodextrin. These new delivery systems were designed to work better in the body by improving how well the mushroom’s active ingredients dissolve and stay stable. Testing showed these enhanced formulations were very effective at fighting bacteria, protecting cells from damage, and killing cancer cells.

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Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

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Scientists are exploring nano-graphene oxide, a microscopic material made from graphene, as a new treatment for serious lung fungal infections. These tiny particles can kill fungal cells through multiple mechanisms and deliver antifungal drugs directly to infection sites while reducing harmful side effects. Researchers found that graphene oxide can be combined with existing antifungal medications to make them work better and even help overcome drug-resistant fungal infections.

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