Dermatology – Page 4

Disseminated subcutaneous sporotrichosis in an immunocompetent patient: A case report and a systematic literature review

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A 74-year-old man developed painful red masses on his arm and hand after being stuck by a tree branch. Tests identified the infection was caused by a fungus called Sporothrix schenckii. Despite having a normal immune system, the infection had spread across his arm in an unusual pattern. Treatment with an antifungal medication called itraconazole completely healed the lesions within four months without any scarring.

Coexistence of Malassezia Species and Microsporum canis in the Lesions of Adult with Tinea Capitis

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A 60-year-old woman developed unusual hair loss and scalp inflammation that looked like dandruff but was actually a fungal infection caused by multiple fungi working together. Doctors found three different fungi in her scalp samples: one dermatophyte and two Malassezia species. Lab experiments showed that the Malassezia fungi actually helped the main disease-causing fungus grow better, which explains why the condition looked different from typical cases. After three months of antifungal medication, her symptoms cleared and her hair grew back.

Deep Fungal Infection of the Skin with Two Rare Fungi in a Dog Being Treated with Immunosuppressant Therapy: A Case Report

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A dog being treated for brain inflammation with immune-suppressing drugs developed a serious skin infection caused by two unusual fungi not previously reported together in veterinary medicine. The infection proved difficult to diagnose, requiring tissue samples and specialized laboratory testing to identify the fungi and determine which antifungal drugs would work best. Despite treatment with antifungal medications and reducing the immunosuppressive drugs, the infection did not improve and the dog’s underlying condition worsened, ultimately requiring euthanasia. This case shows the serious risks of fungal infections in animals on long-term immunosuppressive therapy and highlights the need for careful monitoring and early detection.

Shifting etiological agents of dermatophytosis: a molecular epidemiological study from Iran

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Researchers in Iran studied fungal infections of the scalp and nails using modern DNA testing methods. They found that the main fungus causing scalp infections (T. tonsurans) remains the most common, but a new species (T. indotineae) is increasingly causing nail infections and is resistant to common antifungal medicines. The study shows that traditional identification methods often misidentify these fungi, highlighting the importance of molecular testing for accurate diagnosis and treatment.

Simplicillium sinense sp. nov., a novel potential pathogen of tinea faciei

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Researchers identified a new fungal species called Simplicillium sinense that caused a facial skin infection (tinea faciei) in a 46-year-old man with diabetes. The fungus was resistant to most common antifungal medications but responded well to terbinafine treatment. This is the first reported case of a Simplicillium infection causing facial ringworm, expanding our understanding of rare fungal pathogens.

Prevalence of Tinea pedis in military personnel: a systematic review and meta-analysis

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Athlete’s foot is a common fungal infection affecting military personnel at rates around 17% globally. Military environments create perfect conditions for this infection through close living quarters, humidity from sweat and boots, and shared facilities. The study found that regions with hot, humid climates have higher infection rates, and proper diagnosis using both microscopy and culture tests is important for accurate detection. Improved hygiene, better-designed footwear, and access to antifungal treatments can significantly reduce infection rates in military settings.

Extensive erythematous plaques of fungal origin in an overseas student: Cutaneous manifestation of coccidioidomycosis

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A 21-year-old student studying in Arizona developed unusual skin rashes months after returning to China. Doctors had difficulty diagnosing the condition because it lacked typical symptoms of the fungal infection coccidioidomycosis. By using multiple diagnostic methods including DNA sequencing and fungal culture, they identified the infection as caused by Coccidioides posadasii. When the initial antifungal drug didn’t work, testing showed the fungus was resistant, so they switched to a different antifungal called voriconazole, which successfully cured the infection after 12 months.

Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed

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A 37-year-old construction worker developed unusual scaling and itchy sores around his mouth that worsened despite treatment for eczema. Doctors eventually discovered the infection was caused by a rare yeast fungus called Naganishia albidus, which is almost never seen in healthy people. Using advanced laboratory tests and antifungal medications taken by mouth and applied to the skin, the infection completely cleared within six weeks.

Deep Fungal Infection of the Skin with Two Rare Fungi in a Dog Being Treated with Immunosuppressant Therapy: A Case Report

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An 8-year-old dog receiving long-term immunosuppressive medication for brain inflammation developed rare fungal skin infections caused by two unusual fungi not previously reported together in veterinary medicine. Diagnosis required multiple tests including tissue samples, staining techniques, and genetic testing. Despite treatment with antifungal medications and careful adjustment of immunosuppressive drugs, the infections did not improve, highlighting the difficult balance between fighting infections and controlling the underlying immune disease.

Dermatophyte Treatment Failure: A Rapid Global Response to an Emerging Global Health Issue

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Fungal skin infections affect nearly a billion people worldwide and are becoming increasingly difficult to treat due to growing resistance to common antifungal medications. A new species of fungus called T. indotineae, particularly resistant to the popular antifungal drug terbinafine, is spreading globally from India. To combat this emerging health crisis, doctors and health organizations are working together to create global registries and surveillance programs to track resistant infections and develop better treatment strategies.

Research Topic: Dermatology