Research Topic: CRISPR-Cas9 gene editing

Microbe Profile: Streptomyces formicae KY5: an ANT-ibiotic factory

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Scientists have discovered a special bacterium called Streptomyces formicae that lives in ant nests and produces powerful antibiotics. This bacterium makes formicamycins, which can kill dangerous bacteria like methicillin-resistant Staphylococcus aureus that resists many common antibiotics. Using advanced genetic tools, researchers can modify this bacterium to unlock hidden antibiotic-producing pathways, potentially leading to new medicines to fight drug-resistant infections.

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Gene fusion and functional diversification of P450 genes facilitate thermophilic fungal adaptation to temperature change

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Researchers discovered that a thermophilic fungus uses two special genes to adapt to temperature changes. One of these genes is uniquely fused from two different genes, creating a hybrid protein with multiple functions. These genes help the fungus produce iron-binding molecules that stabilize its structure and support its growth when temperatures drop, allowing the fungus to survive in environments from compost piles to stored grains.

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