Research Topic: cell culture

Neuroprotective Effect of Mixed Mushroom Mycelia Extract on Neurotoxicity and Neuroinflammation via Regulation of ROS-Induced Oxidative Stress in PC12 and BV2 Cells

A mixture of three medicinal mushrooms (Phellinus linteus, Ganoderma lucidum, and Inonotus obliquus) was tested for its ability to protect nerve cells from damage. The extract successfully reduced cell death in laboratory models of neurodegeneration by reducing harmful molecules called reactive oxygen species and reducing inflammation. These results suggest the mushroom extract could potentially help prevent or slow neurological diseases like Alzheimer’s.

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Edible mycelium as proliferation and differentiation support for anchorage-dependent animal cells in cultivated meat production

Scientists developed a new technology using edible mushroom mycelium (the root-like structure of fungi) as a scaffold to grow animal muscle cells for cultivated meat production. They tested different fungal species and found that mycelium from koji mold (Aspergillus oryzae) worked best for supporting cell growth and maturation. Unlike current plastic microcarriers that must be removed from the final product, these edible carriers can be incorporated directly into the meat, adding nutritional value and reducing waste.

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