Research Topic: Biotechnology

From Nature to Design: Tailoring Pure Mycelial Materials for the Needs of Tomorrow

Scientists are developing new materials made from mushroom mycelium that could replace leather, foam, and plastic products. These fungal-based materials grow on simple agricultural waste, are completely biodegradable, and have a much smaller environmental footprint than traditional materials. Companies like MycoWorks are already producing mycelium leather for major fashion brands, showing this technology is moving from laboratories into real products.

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Vermiculite as a new carrier for extracellular protease production by Aspergillus spp. under solid-state fermentation

Researchers discovered that vermiculite, a naturally occurring mineral, is an excellent material for growing fungi that produce proteases—enzymes used in medicine, laundry detergents, and food processing. When Aspergillus fungi were grown on vermiculite using a technique called solid-state fermentation, they produced 3 to 18 times more protease than when grown on other materials. This discovery could make enzyme production more efficient and cost-effective for industrial applications.

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Extremely chaotolerant and kosmotolerant Aspergillus atacamensis – a metabolically versatile fungus suitable for recalcitrant biosolid treatment

Scientists discovered a special fungus called Aspergillus atacamensis that can survive in extremely salty environments, similar to salt lakes in the Atacama Desert. This fungus is remarkable because it can break down harmful pollutants and chemicals, including medications and oil-based compounds. Researchers tested its ability to clean contaminated wastewater and biosolids, finding it highly effective at removing various contaminants. This discovery opens new possibilities for using this hardy fungus to clean up environmental pollution in industries and wastewater treatment facilities.

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Development of Leather-like Materials from Enzymatically Treated Green Kiwi Peel and Valorization of By-Products for Microbial Bioprocesses

This research shows how kiwi fruit peels, normally discarded as waste, can be transformed into leather-like materials through enzymatic treatment. The study found that treating the peels with commercial enzymes produced flexible, durable films with properties comparable to traditional leather, while the leftover liquid from the treatment process could be used to grow industrially useful yeast cultures. This integrated approach demonstrates how agro-food waste can be completely recycled into valuable products, supporting sustainable manufacturing practices.

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Indigenizing fungal biotechnology for planetary health: an opinion paper

This paper proposes a framework for using fungi in sustainable ways that respects Indigenous Peoples’ knowledge and rights. Rather than large corporations controlling fungal biotechnology, the authors suggest local communities should develop their own fungal products using local species and waste materials. By combining traditional Indigenous practices with modern biotechnology and digital tools, communities can grow food, medicines, and materials while protecting fungal biodiversity and sharing in the economic benefits.

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Exploring Bioactive Compounds from Fruit and Vegetable By-Products with Potential for Food and Nutraceutical Applications

This review explores how food waste from fruit and vegetable processing can be transformed into valuable health supplements and functional foods. By-products like peels, seeds, and leaves contain powerful compounds with antioxidant and anti-inflammatory properties. Modern extraction techniques can efficiently recover these compounds in environmentally friendly ways, making it possible to create nutritious supplements while reducing food waste and supporting sustainable food production.

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Strategy of employing plug-and-play vectors and LC–MS screening to facilitate the discovery of natural products using Aspergillus oryzae

Researchers developed new tools to make it faster and easier to discover useful compounds from fungi. They created improved genetic vectors that allow scientists to insert multiple genes into Aspergillus oryzae more conveniently, and developed a quick screening method using mass spectrometry to identify successful transformants directly on culture plates. This approach saves about 10 days compared to traditional methods, significantly accelerating the discovery of new natural products with potential medical and agricultural applications.

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Tailoring the Mechanical Properties of Fungal Mycelium Mats with Material Extrusion Additive Manufacturing of PHBH and PLA Biopolymers

Researchers developed a new way to make fungal mushroom mats stronger by printing biodegradable plastic patterns onto them using 3D printing technology. The resulting composite materials combined the sustainability of fungal products with improved strength, making them suitable for flexible applications like smart textiles and lightweight parts. Both tested polymers (PHBH and PLA) enhanced the mycelium’s mechanical properties, with PLA showing superior strength improvements while PHBH offered home compostability.

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Towards engineering agaricomycete fungi for terpenoid production

Mushroom-forming fungi, particularly species like shiitake and oyster mushrooms, naturally produce valuable compounds called terpenoids used in medicines, food, and cosmetics. Scientists are learning to genetically engineer these fungi to produce even larger amounts of these beneficial compounds, potentially making them as important to biotechnology as baker’s yeast and mold have been historically. This could create new sustainable sources for medicinal compounds and industrial chemicals.

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Fusiform nanoparticle boosts efficient genetic transformation in Sclerotinia sclerotiorum

Scientists developed a new method using tiny fusiform nanoparticles to introduce genes into a destructive plant fungus called Sclerotinia sclerotiorum. This approach is simpler and faster than traditional genetic engineering methods because it doesn’t require complex cell preparation steps. The research shows that by silencing specific fungal genes, they could reduce the fungus’s ability to cause disease, which could help develop better strategies to protect crops like rapeseed and soybean.

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