Research Topic: bioactive compounds

Inhibitory Activity of Shrimp Waste Extracts on Fungal and Oomycete Plant Pathogens

Researchers discovered that waste from shrimp processing can be converted into a natural fungicide that effectively kills plant-damaging fungi and mold. When applied to oranges, lemons, and apples artificially infected with mold, the shrimp waste extract significantly reduced rot and fruit damage. This finding is important because it offers a more environmentally friendly alternative to chemical fungicides while helping reduce the massive amounts of shrimp processing waste that typically end up in landfills or oceans.

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Unveiling the Therapeutic Potentials of Mushroom Bioactive Compounds in Alzheimer’s Disease

Mushrooms contain special compounds that may help protect the brain from Alzheimer’s disease. Research shows that eating mushrooms regularly could reduce the risk of memory problems and cognitive decline in older adults. These compounds work by reducing brain inflammation, protecting nerve cells, and helping the brain clear out harmful proteins. While these findings are promising, more human studies are needed to confirm how effective mushrooms are as an Alzheimer’s treatment.

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Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (Agaricus bisporus)

Researchers discovered a new compound in white button mushrooms called 2-amino-4-methylbenzothiazole that activates the aryl hydrocarbon receptor, which helps regulate gut health and immunity. Using a computational approach called molecular networking to compare mushroom compounds with known beneficial substances, scientists identified this previously unknown compound and confirmed its activity in laboratory cells. This discovery demonstrates how certain mushrooms may contribute to health through specific bioactive compounds and provides a faster method for finding similar compounds in other foods.

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Edible Mushrooms as Functional Ingredients for Development of Healthier and More Sustainable Muscle Foods: A Flexitarian Approach

This comprehensive review explains how edible mushrooms can be added to meat and fish products to make them healthier and more environmentally friendly. Mushrooms are rich in protein, fiber, vitamins, and natural compounds that fight disease and prevent spoilage. By replacing part of the meat with mushrooms, food makers can create products with better nutrition, longer shelf-life, and reduced salt content, while supporting those pursuing flexitarian diets.

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Assessment of Cosmetic Properties and Safety of Use of Model Washing Gels with Reishi, Maitake and Lion’s Mane Extracts

Researchers tested three medicinal mushrooms (Maitake, Lion’s Mane, and Reishi) as ingredients in washing gels to improve their safety and effectiveness. The study found that these mushroom extracts reduced skin irritation, improved skin moisturization, and boosted antioxidant protection better than gels without them. Maitake extract performed particularly well, showing the strongest antioxidant properties. These findings suggest mushroom extracts could be valuable natural alternatives in everyday skincare products.

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The treasured giants: a current overview on agricultural, nutritional, bioactive, and economic potential of Macrocybe Species (Agaricales, Basidiomycota)

Macrocybe mushrooms are giant edible fungi found in tropical regions worldwide that offer significant nutritional and health benefits. These mushrooms can be cultivated using agricultural waste materials like sawdust and straw, making them an economical crop. Rich in proteins, fibers, vitamins, and medicinal compounds, they possess antimicrobial and immune-boosting properties that could benefit human health.

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Revitalization of the Endophytic Fungus Acremonium sp. MEP2000 and Its Impact on the Growth and Accumulation of Bioactive Compounds in Inonotus obliquus

Researchers successfully revived a beneficial fungus called Acremonium sp. MEP2000 that had lost its effectiveness through repeated cultivation by adding birch bark powder and medicinal mushroom powder to its growth medium. When used to treat the medicinal fungus Inonotus obliquus (chaga), this revitalized fungal culture dramatically improved the growth and production of healthy bioactive compounds like polysaccharides and triterpenoids. This breakthrough offers a practical solution for large-scale production of medicinal fungi with enhanced therapeutic potential for treating cancer, diabetes, and inflammatory conditions.

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Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

Mushrooms have been used for health for thousands of years and contain special compounds that help boost the immune system and fight cancer. Scientists have identified several key active ingredients in mushrooms like polysaccharides and proteins that can activate immune cells and reduce tumors. Some mushroom products like lentinan from shiitake mushrooms have already been approved as cancer treatments in Japan. While most evidence comes from lab studies, ongoing research suggests mushroom-based medicines could become important therapeutic options.

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Emerging Nonthermal Technologies for the Production of Postbiotics

Postbiotics are dead or inactivated beneficial microorganisms and their components that support human health without needing to survive in the gut. Traditional heat-killing methods damage these beneficial compounds. This comprehensive review explores six emerging technologies that can produce postbiotics while better preserving their health-promoting properties, making them more stable and effective for food and supplement applications.

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Immune regulatory functions of biologically active proteins from edible fungi

This research compared how proteins from 22 different edible mushrooms affect immune system cells called macrophages. The study found that all the mushroom proteins tested boosted immune function by making macrophages more active and productive. Interestingly, expensive rare mushrooms like cordyceps and ganoderma lucidum had stronger immune-boosting effects than common grocery store mushrooms like oyster and button mushrooms.

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