Research Topic: antioxidants

Biologically active secondary metabolites from white-rot fungi

White-rot fungi are special mushrooms that can break down wood and produce unique chemical compounds with amazing health benefits. These compounds have been found to fight cancer, kill harmful bacteria, reduce inflammation, and protect nerve cells. Scientists are excited about using these natural fungal compounds to create new medicines and treat various diseases in the future.

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Dynamic changes of nutrients, isoflavone composition and antioxidant activities during liquid-state fermentation of soybean embryo homogenate by Ganoderma lucidum

Researchers fermented soybean embryo using Ganoderma lucidum mushroom to create a more nutritious and better-tasting food product. During fermentation, the mushroom’s enzymes broke down hard-to-digest compounds and converted isoflavones into more absorbable forms while dramatically increasing antioxidant activity. The fermented product showed 8-fold higher antioxidant power and reduced unpleasant flavors, making soybean embryo a viable functional food ingredient.

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Therapeutic and Preventive Potential of Plant-Derived Antioxidant Nutraceuticals

This comprehensive review explores how compounds found in plants can protect our bodies from harmful damage caused by oxidative stress, which is linked to aging and various diseases. Plant-based foods rich in antioxidants like berries, leafy greens, and olive oil contain special molecules that can help prevent cancer, heart disease, diabetes, and other chronic conditions. The review highlights that these natural compounds work through multiple beneficial mechanisms beyond just antioxidant activity, making plant-based diets an effective strategy for maintaining health and preventing disease.

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The Benefits of a Multimechanistic Antiaging Skin Technology

Researchers tested a special antiaging face serum containing multiple skin-boosting ingredients on 50 women over 24 weeks. The serum significantly improved skin hydration, firmness, texture, and reduced wrinkles and fine lines. Results showed improvements as early as one week, with continued benefits throughout the study, and the product was very well tolerated with no irritation or side effects.

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Oxidative Stress in Spinocerebellar Ataxia Type 3 and Its Attenuation by Herbal Remedies in Traditional Chinese Medicine: A Systematic Review

Spinocerebellar ataxia type 3 is a serious brain disease that causes movement problems and gets worse over time. Current medications help but often have unpleasant side effects. This review examined fifteen traditional Chinese herbal remedies that show promise in protecting nerve cells from damage caused by oxidative stress, a harmful chemical process in the body. These herbs work through multiple protective mechanisms and may eventually be tested in patients.

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Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

Scientists created tiny particles called zinc oxide nanoparticles using mushroom extract in an environmentally friendly way. These particles were tested and found to protect the liver from damage, kill harmful bacteria and fungi, and act as powerful antioxidants. This research suggests these mushroom-derived nanoparticles could become useful medicines for treating infections and cancer in the future.

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Association of mushroom consumption with all-cause and cause-specific mortality among American adults: prospective cohort study findings from NHANES III

This study followed over 15,000 American adults for nearly 20 years and found that people who ate mushrooms had a lower risk of dying from any cause compared to those who didn’t eat mushrooms. The more mushrooms people ate, the greater the benefit. Replacing red or processed meat with mushrooms was associated with even greater longevity benefits. Mushrooms’ beneficial effects likely come from their high antioxidant content, particularly compounds called ergothioneine and glutathione.

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Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

Morel mushrooms lose quality when repeatedly cultured in laboratories, becoming slower-growing and less vibrant. Scientists discovered this happens because genes controlling antioxidant production shut down, allowing harmful free radicals to damage cells. By avoiding frequent subculturing and using cold storage or antioxidant supplements, farmers can keep their morel strains healthy and productive for longer.

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A Systematic Review on Important Risk Factors and Possible Involved Mechanisms of Medicinal Plants on Nonalcoholic Fatty Liver Disease

This comprehensive review examined 43 medicinal plants that can help prevent and treat fatty liver disease (NAFLD), which is increasingly common in developed countries. Most of these plants work by reducing cholesterol and triglycerides, helping with weight management, improving blood sugar control, and lowering blood pressure. The plants contain natural compounds like flavonoids and polyphenols that reduce inflammation and oxidative stress in the liver. Using these herbal supplements alongside other lifestyle changes may offer a promising natural approach to managing NAFLD and its related conditions.

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Extraction of Active Compounds from Dioscorea quinqueloba and Their Encapsulation Using Mucin and Chitosan for Application in Cosmetic Formulations

Researchers created tiny capsules containing beneficial compounds from yam plants using natural materials like chitosan and mucin, designed for use in cosmetic products. These microcapsules were shown to be safe, effective at protecting skin from oxidative damage, and capable of reducing signs of aging similar to green tea extract. The study demonstrates that yam-based microcapsules have strong potential as natural ingredients in skincare formulations.

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