Research Topic: antioxidant activity

Mycochemistry, antioxidant activity and anticancer potentiality of ethyl acetate extract of Daldinia eschscholtzii against A549 lung cancer cell line

Researchers studied a wild fungus called Daldinia eschscholtzii to see if it could fight lung cancer. They found that an extract from this fungus contained 28 different beneficial compounds and was effective at killing cancer cells by triggering a process called apoptosis (programmed cell death). The treatment also reduced the cancer cells’ ability to spread, and it appeared safe for normal, healthy cells. Several compounds in the extract showed promise as potential anti-cancer drugs.

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Chemical Composition and In Vitro Biological Activity of the Polar and Non-Polar Fractions Obtained from the Roots of Eleutherococcus senticosus (Rupr. et Maxim.) Maxim

Siberian ginseng (Eleutherococcus senticosus) roots contain powerful antioxidant compounds that may help with inflammation, blood sugar control, and brain health. Researchers found that certain plant fractions were particularly rich in protective compounds like chlorogenic acid and caffeic acid. However, the study also discovered a concerning finding: these plant compounds protected cancer cells from chemotherapy drugs, suggesting people undergoing cancer treatment should be cautious about using this supplement.

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Research advances in fungal polysaccharides: production, extraction, characterization, properties, and their multifaceted applications

This comprehensive review examines fungal polysaccharides, which are complex sugar molecules found in mushrooms and fungi that have powerful health benefits. Researchers describe how to grow and extract these compounds from various fungi, and explain their uses in treating diseases like cancer, reducing inflammation, and boosting immunity. The review covers different growing and extraction methods used worldwide and discusses future directions for using these natural compounds in medicine and industry.

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Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand

This research studied five types of oyster mushrooms grown in Thailand at different stages of maturity. Researchers found that the nutritional content and beneficial compounds in mushrooms change as they grow. Young and middle-stage mushrooms had the highest levels of compounds that fight disease and help manage blood sugar, while fully mature mushrooms had more total nutrients. This information helps farmers decide when to harvest mushrooms based on whether customers want maximum nutrition or maximum health-promoting properties.

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Potential of traditional Chinese medicine in gastrointestinal disorders: Hericium erinaceus in chronic atrophic gastritis

Lion’s Mane mushroom (Hericium erinaceus) shows promise for treating chronic stomach inflammation and preventing gastric cancer. Studies indicate it can reduce stomach pain, improve endoscopic findings, and fight harmful bacteria like H. pylori. Its active compounds work by reducing inflammation, oxidative stress, and promoting cancer cell death, offering a natural complement to conventional treatments.

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Chemical Composition, Bioactive Compounds, and Antioxidant Activity of Two Wild Edible Mushrooms Armillaria mellea and Macrolepiota procera from Two Countries (Morocco and Portugal)

This study compared two edible wild mushrooms (honey fungus and parasol mushroom) from Morocco and Portugal to understand their health benefits. Both mushrooms were found to be rich in compounds with antioxidant properties that help protect cells from damage. The research shows that where mushrooms grow—whether in Morocco or Portugal—affects their chemical makeup and healing potential, with Moroccan honey fungus showing particularly strong antioxidant power.

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Flammulina velutipes stem regulates oxidative damage and synthesis of yolk precursors in aging laying hens by regulating the liver–blood–ovary axis

This study shows that adding golden needle mushroom stems to the feed of aging laying hens improves egg production by reducing oxidative damage and boosting reproductive hormones. The mushroom stem, normally a waste product, works through a liver-ovary signaling pathway to enhance the production of yolk-building proteins and improve the quality and number of developing eggs. The treatment was particularly effective at doses of 4-6% supplementation and also had beneficial side effects like reducing abdominal fat and improving eggshell thickness.

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Ganoderma lucidum inspired silver nanoparticles and its biomedical applications with special reference to drug resistant Escherichia coli isolates from CAUTI

Researchers created tiny silver particles using a medicinal mushroom called Ganoderma lucidum to fight dangerous bacteria that resist antibiotics and are associated with urinary catheter infections. These nanoparticles were found to effectively kill drug-resistant bacteria, work as antioxidants better than a common antioxidant standard, and showed promise in killing breast cancer cells. This eco-friendly approach offers a natural alternative to conventional antibiotics for treating serious antibiotic-resistant infections.

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Enhancing Nutritional Quality and Functionality of Legumes: Application of Solid-State Fermentation With Pleurotus ostreatus

Researchers used a mushroom fungus (Pleurotus ostreatus) to ferment lentils, chickpeas, and soybeans, making them more nutritious and easier for the body to digest. The fermentation process reduced harmful compounds called antinutrients while boosting protein content and antioxidant power. This simple bioprocessing method could help create healthier plant-based foods that rival animal protein sources in nutritional quality.

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Assessment of Cucurbita spp. Peel Extracts as Potential Sources of Active Substances for Skin Care and Dermatology

This study examined pumpkin peels as a sustainable source of natural compounds for skincare products. Researchers extracted active ingredients using water and plant-based solvents, then tested their antioxidant properties, ability to protect skin from sun damage, and safety for use on skin. The findings show that pumpkin peel extracts, particularly those made with water, could be safe and effective ingredients in cosmetic products.

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