Research Topic: antioxidant activity

Artificial intelligence-assisted optimization of extraction enhances the biological activity of Phylloporia ribis

Scientists optimized how to extract beneficial compounds from Phylloporia ribis mushrooms using artificial intelligence, finding that an AI-assisted method produced extracts with stronger antioxidant power and cancer-fighting properties than traditional statistical approaches. The optimized extracts showed promise in fighting free radicals, potentially supporting brain health against Alzheimer’s disease, and slowing cancer cell growth. This research demonstrates how combining mushroom extraction with modern AI technology could lead to more effective natural medicines.

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Diversity and bioprospecting activities of endophytic Fungi associated with different Egyptian medicinal plants

Scientists studied fungi that live inside Egyptian medicinal plants and found that one type called Aspergillus terreus produces compounds with powerful healing properties. These compounds can fight harmful bacteria, reduce oxidative damage, and even kill cancer cells while being safe for normal cells. This discovery suggests that fungi living in medicinal plants could be valuable sources of new medicines, offering hope for developing new treatments for infections and cancer.

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Ultrasound-Assisted Preparation of Chitosan Oligosaccharide-Stabilized Thyme Oil-in-Water Nanoemulsions: Enhanced Storage Stability and Antimicrobial Properties

Researchers created tiny droplets of thyme oil mixed in water using sound waves and a natural stabilizer from shellfish shells. These droplets stayed stable for weeks without separating and worked twice as well at fighting bacteria and mold compared to regular thyme oil. The new formula could be used to keep fresh food from spoiling during storage.

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Optimization of Ultrasonic Extraction to Obtain Erinacine A and Polyphenols with Antioxidant Activity from the Fungal Biomass of Hericium erinaceus

Researchers developed an efficient ultrasonic extraction method to obtain beneficial compounds from the lion’s mane mushroom (Hericium erinaceus), particularly a substance called erinacine A and antioxidants. The optimized process uses 80% ethanol and takes 45 minutes, producing extracts rich in antioxidants that can protect cells from damage. These extracts showed promise in protecting brain cells and could potentially help prevent or treat neurodegenerative diseases like Alzheimer’s disease.

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Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

This review explores how medicinal mushrooms, particularly Cerrena unicolor, can be used to improve health through functional foods and supplements. The mushroom contains natural compounds with powerful properties including fighting cancer cells, killing harmful bacteria and viruses, and protecting the body from oxidative stress. Research shows these mushrooms could be incorporated into dairy products and other foods to create innovative health-promoting products for consumers.

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Anoectochilus roxburghii Extract Extends the Lifespan of Caenorhabditis elegans through Activating the daf-16/FoxO Pathway

Researchers studied a traditional Asian orchid plant (Anoectochilus roxburghii) and found it can extend the lifespan of laboratory worms by about 16% and help them resist stress from UV light and heat. The plant works by activating a specific genetic pathway that increases the worm’s natural antioxidant defenses, protecting cells from damage. These findings suggest the plant could potentially be developed into anti-aging products for humans.

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From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

This research examined reishi mushroom (Ganoderma lucidum), a traditional medicinal fungus, to find rare compounds called depsidones with potential cancer-fighting properties. Scientists extracted these compounds using different solvents and tested them against four types of cancer cells (liver, colon, breast, and lung cancer), finding that they successfully killed cancer cells while being safe to normal cells. Using advanced chemical analysis and computer modeling, they identified nine new depsidone compounds in reishi and showed how these compounds could bind to cancer-related proteins to stop tumor growth.

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Structure and Bioactivity of Intracellular and Extracellular Polysaccharides of Trametes lactinea Mycelium

Researchers extracted and studied polysaccharides from Trametes lactinea mushroom mycelium grown in liquid culture. They found that these polysaccharides have strong antioxidant properties and can boost immune cell function, with the intracellular polysaccharide IP-3 showing the most promising results. These findings suggest that polysaccharides from mushroom fermentation could have potential health benefits and could be developed into medicinal supplements.

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Isolation and Antioxidant Mechanism of Polyphenols from Sanghuangporous vaninii

Researchers found that a medicinal mushroom called Sanghuangporous vaninii grown on mulberry sawdust in China contains exceptionally high levels of polyphenols—powerful antioxidant compounds. They isolated and purified a particularly potent polyphenol mixture called HNMS3, which contains 33 different compounds. Through advanced molecular analysis, they discovered that HNMS3 works by activating eight key proteins in the body to fight oxidative stress, making it potentially beneficial for brain health and preventing nerve degeneration.

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Assessment of the Antitumor Activity of Green Biosynthesized Zinc Nanoparticles as Therapeutic Agent Against Renal Cancer in Rats

Researchers created tiny zinc nanoparticles using an edible white mushroom through an environmentally friendly process. When tested in rats with kidney cancer, these nanoparticles significantly reduced tumor markers, protected kidney cells from oxidative damage, and triggered cancer cell death. The treatment improved kidney function and showed no toxic effects, suggesting it could be a promising new therapy for kidney cancer.

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