Research Topic: antimicrobial activity

Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

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Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles

Periodontitis is a serious gum disease that causes tooth loss and affects overall health. This review examines how polysaccharides (complex carbohydrates) from plants and fungi can help treat periodontitis by reducing inflammation, fighting bacteria, and helping gum tissue repair. These natural compounds work through multiple biological pathways to improve oral health outcomes while avoiding the side effects and resistance problems associated with conventional drugs.

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Advancing Pistacia terebinthus L. (Anacardiaceae) Research: Food Preservation, Functional Foods, and Nutraceutical Potential

The turpentine tree (Pistacia terebinthus L.) is a Mediterranean plant traditionally used in food and medicine that is now being studied for modern food applications. Its fruits, seeds, leaves, and resin contain powerful compounds that fight bacteria, reduce oxidative stress, and promote health. Scientists are developing new techniques like microencapsulation and fermentation to preserve its beneficial properties in functional foods, yogurt, and other products. This underutilized plant could become an important natural ingredient for food preservation and health supplements.

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Exploring the Bioactive Potential of Calostoma insigne, an Endangered Culinary Puffball Mushroom, from Northeastern Thailand

This research investigated a rare, eye-shaped mushroom called Calostoma insigne that grows in Thai rainforests and is eaten by local people. Scientists confirmed traditional beliefs that the mushroom has health benefits, discovering it has antioxidant, anti-cancer, and anti-diabetic properties. The study also determined the best way to grow this mushroom in laboratories, which could help conserve the endangered species while providing a sustainable food and health resource.

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Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives

This comprehensive review examined what we know about Psilocybe mushrooms, which are known for their mind-altering effects due to compounds called psilocybin and psilocin. The study found that while these mushrooms show promise for treating depression and anxiety, most research has focused only on their psychoactive properties. The review identified over 30 chemical compounds in these mushrooms and noted that some species show potential antimicrobial and antioxidant properties. The authors emphasize that much more research is needed to explore other potential health benefits and to understand exactly how individual compounds work in the body.

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Electrospun Membranes Loaded with Melanin Derived from Pecan Nutshell (Carya illinoinensis) Residues for Skin-Care Applications

Researchers developed new skincare membranes by combining pecan shell waste with advanced fiber technology. These membranes harness melanin from the shells to create materials with strong antioxidant and antibacterial properties that could protect skin from aging and infections. The innovation demonstrates how agricultural waste can be transformed into valuable cosmetic products that are both effective and environmentally friendly.

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Exploring the Wound Healing Potential of Hispidin

Hispidin, a natural compound from medicinal mushrooms, shows promise as a wound healing treatment. Research demonstrates that hispidin can kill harmful bacteria, stimulate skin cell growth and migration, reduce inflammation, and improve wound closure when applied as an ointment. The 5% hispidin ointment performed as well as or better than standard wound treatments in rat studies, with no toxic side effects observed, suggesting potential for future wound care products.

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Extraction and Identification of the Bioactive Metabolites Produced by Curvularia inaequalis, an Endophytic Fungus Collected in Iran from Echium khuzistanicum Mozaff

Researchers discovered a fungus living inside an Iranian medicinal plant that produces three natural compounds with powerful antimicrobial properties. The most promising compound, phomalactone, killed dangerous bacteria including MRSA and also prevented growth of fungal plant diseases. This discovery shows that exploring symbiotic fungi in medicinal plants could lead to new natural antibiotics and agricultural fungicides.

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Functionalized Micellar Membranes from Medicinal Mushrooms as Promising Self-Growing Bioscaffolds

Researchers created special membranes from medicinal mushrooms that could be used for wound healing and skin repairs. These membranes were grown in laboratory conditions and then treated with mango peel extract, which gave them antimicrobial properties to fight bacteria. The membranes are biodegradable, environmentally friendly, and work similar to the structure of skin tissue, making them promising for medical applications.

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Adaptation strategies in haloalkaliphilic fungi: Aspergillus salinarum, Cladosporium sphaerospermum, and Penicillium camemberti

Researchers studied three special fungi that can survive in extremely salty and alkaline environments. These fungi adapt to harsh conditions by producing more proteins, fats, and special enzymes that have antimicrobial properties. The findings suggest these fungi could be useful for cleaning contaminated soils, producing medicines, and developing new industrial products.

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