Research Topic: Antifungal activity

Antifungal Activity of Industrial Bacillus Strains against Mycogone perniciosa, the Causative Agent of Wet Bubble Disease in White Button Mushrooms

Researchers tested two special bacteria strains (Bacillus subtilis B-10 and M-22) to protect white button mushrooms from wet bubble disease, a serious fungal infection that can destroy entire crops. When applied to mushroom growing beds, both bacteria effectively prevented the disease-causing fungus from developing, with success rates between 50-99% depending on application method. This offers mushroom farmers a natural, chemical-free alternative to synthetic fungicides for protecting their crops.

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Antifungal and other bioactive properties of the volatilome of Streptomyces scabiei

Researchers discovered that Streptomyces scabiei, a bacterium known for causing common scab disease on potatoes and other root vegetables, produces various airborne chemicals with surprising benefits. Using advanced laboratory techniques, scientists identified 36 different volatile compounds from this bacterium, many of which can kill harmful fungi and potentially help plants grow better. While traditionally viewed as purely harmful, these findings suggest the bacterium may actually serve a more complex role in soil, sometimes protecting crops from more dangerous diseases.

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Sunlight-sensitive carbon dots for plant immunity priming and pathogen defence

Scientists developed special tiny carbon particles that respond to sunlight by producing molecules that strengthen plant defenses against fungi. When sprayed on plants like tomato and tobacco, these particles trigger the plant’s natural immune system, reducing fungal diseases by 12-44% without harming the plant. At higher concentrations with continuous sunlight, the particles can directly kill fungal pathogens. This eco-friendly approach offers a sustainable alternative to chemical fungicides while maintaining crop yields.

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Chemical profile and bioactivity of essential oils from five Turkish thyme species against white mold fungal disease agent Sclerotinia sclerotiorum

Researchers tested essential oils from five different thyme species grown in Turkey against a common plant fungus that causes white mold disease. They found that oils rich in carvacrol, particularly from Thymbra spicata and Satureja cilicica, were very effective at stopping fungal growth. These natural oils could be used as environmentally friendly alternatives to chemical pesticides in farming.

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Neem Essential Oil as an Antifungal Agent against Phyllosticta citricarpa

Citrus fruits are susceptible to a serious fungal disease called black spot that prevents them from being exported to certain countries. This study tested neem oil, a natural plant extract, as a replacement for chemical fungicides currently used to clean citrus fruits. The researchers found that neem oil was just as effective as the standard copper-based treatments at killing the fungus and preventing the disease, and it worked by breaking down the fungus cell membranes. This natural alternative could help farmers and fruit companies maintain food safety while using more eco-friendly solutions.

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Inhibitory effect and mechanism of action of Carvacrol as a promising natural food preservative against Fusarium acuminatum causing postharvest rot of garlic scapes (Allium sativum L)

Garlic scapes often rot quickly during storage due to fungal infections. This study found that carvacrol, a natural compound from oregano and thyme, effectively prevents this spoilage and extends shelf life. The research showed that carvacrol damages the fungal cells’ protective membranes, stopping the infection. Since carvacrol is already approved as safe for food use, it could become a practical, natural alternative to chemical preservatives.

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Synergistic potential and apoptosis induction of Bunium persicum essential oil and its pure components, cuminaldehyde and γ-terpinene, in combination with fluconazole on Candida albicans isolates: in vitro and in silico evaluation

Researchers studied how Bunium persicum essential oil and two of its active components work together with the antifungal drug fluconazole to fight resistant Candida yeast infections. They found that cuminaldehyde, one of the oil’s main components, was particularly effective when combined with fluconazole and could trigger yeast cell death. These natural compounds could offer a promising new approach to treating fungal infections that have become resistant to standard medications.

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Transcriptome Analysis of Dimethyl Fumarate Inhibiting the Growth of Aspergillus carbonarius

Researchers found that dimethyl fumarate, a chemical preservative, can effectively stop the growth of a common fruit fungus called Aspergillus carbonarius that causes rot and produces a harmful toxin in grapes. By studying how the fungus responds to this treatment at the genetic level, scientists discovered that the chemical damages the fungus’s protective outer layer and interferes with its ability to develop and reproduce. This research could lead to better ways to preserve fruit and prevent toxin contamination in the food industry.

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Essential Oils as an Antifungal Alternative for the Control of Various Species of Fungi Isolated from Musa paradisiaca: Part I

Researchers tested six essential oils from common kitchen herbs to see if they could prevent banana spoilage caused by fungi. They found that cinnamon oil was especially effective, stopping fungal growth at relatively low concentrations. This research suggests that natural essential oils could replace harsh chemical fungicides in farming, making bananas safer for consumers and better for the environment.

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Terpinen-4-ol triggers autophagy activation and metacaspase-dependent apoptosis against Botrytis cinerea

Terpinen-4-ol, a natural compound from tea tree oil, effectively kills gray mold fungus that spoils fruits and vegetables after harvest. The compound works by damaging fungal cell membranes, creating harmful reactive molecules inside fungal cells, and triggering the fungal cells’ self-destruction pathways. When tested on tomatoes and strawberries, terpinen-4-ol successfully reduced mold growth and disease spread, suggesting it could be a safe, eco-friendly alternative to chemical fungicides for protecting fresh produce.

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