Research Topic: anticancer compounds

Nutrients and Nutraceuticals from Vitis vinifera L. Pomace: Biological Activities, Valorization, and Potential Applications

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Wine production generates millions of tons of grape pomace (the leftover skins, seeds, and stems) annually, which has traditionally been discarded as waste. This review shows that grape pomace is actually rich in valuable nutrients and compounds like polyphenols and fiber that provide significant health benefits including antioxidant, anti-inflammatory, and disease-fighting properties. By using grape pomace in functional foods, supplements, and cosmetics, the wine industry can reduce waste while creating sustainable products that promote human health.

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How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

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This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

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An Overview of α-Pyrones as Phytotoxins Produced by Plant Pathogen Fungi

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This comprehensive review examines toxic compounds called α-pyrones that are produced by disease-causing fungi affecting crops and plants. These compounds act as natural poisons that help fungi damage plants, but interestingly, they also have potential medical uses including antibacterial, antifungal, and anti-cancer properties. Researchers have studied how the chemical structure of these compounds relates to their toxicity, which could help develop new herbicides for weed control and treatments for various diseases. The review covers dozens of these compounds and their applications in agriculture, medicine, and biotechnology.

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Mushroom Bioactive Molecules as Anticancerous Agents: An Overview

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Mushrooms contain natural compounds that show promise in fighting cancer by triggering cancer cell death and boosting immune function. Different mushroom species like oyster, shiitake, and button mushrooms contain substances such as beta-glucans and other polysaccharides that have demonstrated anticancer properties in laboratory and animal studies. While these mushroom compounds work through multiple mechanisms including preventing new blood vessel formation to tumors and stopping cancer cell division, more human clinical trials are needed to confirm their effectiveness as cancer treatments.

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