Research Topic: air pollution

Lentinan Alleviated PM2.5 Exposure-Induced Epithelial–Mesenchymal Transition in Pulmonary Epithelial Cells by Inhibiting the GARP/TGF-β/Smad Pathway

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Air pollution particles (PM2.5) can cause serious lung damage by triggering a process called epithelial-mesenchymal transition, where lung cells lose their protective qualities. This study found that a natural compound called lentinan, derived from shiitake mushrooms, can help prevent this harmful process by blocking a protein called GARP. The research suggests that lentinan could be a promising natural treatment for lung diseases caused by air pollution.

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Environmental pollution and its impact on hypertension: a review

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This review explains how environmental pollution from cars, factories, and industrial processes contributes to high blood pressure. Various pollutants like fine dust particles, heavy metals, and chemical vapors damage blood vessels and trigger inflammation in the body, leading to hypertension. Women after menopause and older adults are particularly vulnerable to these effects. The review emphasizes the importance of government policies, public education, and personal awareness in reducing pollution exposure and protecting heart health.

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Armillaria mellea Mycelia Alleviate PM2.5-Induced Pulmonary Inflammation in Murine Models

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This study found that Armillaria mellea mushroom mycelia can help protect lungs from damage caused by PM2.5 air pollution. When tested in both laboratory cells and mice, the mushroom extract reduced inflammatory responses and restored healthy lung function. The protective effects work by reducing harmful inflammatory molecules and blocking inflammatory signaling pathways. These findings suggest A. mellea could be developed into a natural supplement to help protect respiratory health in areas with poor air quality.

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