Acceptance and commitment therapy

Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority trial

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This study tests whether psilocybin (the active compound in magic mushrooms) combined with therapy can help people with severe alcohol addiction reduce drinking. Participants receive either a high or low dose of psilocybin during a guided session as part of a hospital rehabilitation program. The researchers will measure changes in drinking behavior, mood, anxiety, and brain function to determine if this treatment works better than current options.

Psychological flexibility as a mechanism of change in psilocybin-assisted therapy for major depression: results from an exploratory placebo-controlled trial

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This study examined how psilocybin mushroom therapy works for treating depression when combined with talk therapy. Participants received a placebo pill followed by psilocybin four weeks later, both times as part of psychological treatment. The research found that people who received psilocybin showed greater improvements in their ability to accept difficult thoughts and emotions and live according to their values, and these improvements were linked to feeling less depressed.

Research Topic: Acceptance and commitment therapy

Psilocybin-assisted therapy for severe alcohol use disorder: protocol for a double-blind, randomized, placebo-controlled, 7-month parallel-group phase II superiority trial

Psychological flexibility as a mechanism of change in psilocybin-assisted therapy for major depression: results from an exploratory placebo-controlled trial