Research Topic: regulatory frameworks

Factors governing consumers buying behavior concerning nutraceutical product

This study examines why people buy nutraceutical products like health supplements and functional foods. Key factors include knowing the health benefits, product taste and packaging, affordability and availability, and recommendations from healthcare professionals. The study found that age, education, and gender affect purchasing decisions, and online shopping has become increasingly important. Companies should focus on innovative products with simple health messages to better serve different consumer groups.

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Fungal biodegradation of chlorinated herbicides: an overview with an emphasis on 2,4-D in Argentina

Fungi can effectively break down and remove harmful herbicides like 2,4-D, which is widely used in Argentine agriculture but poses health and environmental risks. Through their powerful enzymatic machinery, certain fungal species can degrade these toxic chemicals into less harmful substances. This review examines how these fungal degradation processes work and discusses how such fungi might be safely introduced into contaminated environments to clean them up, following Argentina’s regulatory requirements.

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Implementing psychedelic-assisted therapy: History and characteristics of the Swiss limited medical use program

Switzerland operates a unique program allowing controlled use of psychedelics (LSD, psilocybin) and MDMA to help patients with serious mental health conditions that haven’t responded to standard treatments. Since 2014, about 100 doctors have treated 700+ patients with these substances as part of therapy sessions. The program requires careful patient screening, informed consent, and outcome reporting, with patients typically receiving 2-4 treatments over 12 months. Most patients showed significant improvement in their conditions, though some experienced side effects like nausea or headaches.

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Ketamine, Psychedelics, and Psychotherapy: Reframing, Redefining, Renaming Treatment Models

This paper addresses confusion about how ketamine and psychedelics are being used to treat mental health conditions like depression and PTSD. The authors propose new clear definitions to distinguish whether these drugs are used alone for their chemical effects, combined with established talk therapies, or used to create experiences that are then processed in therapy. Using these clearer definitions will help patients, doctors, and regulators better understand what treatments involve and make more informed decisions.

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Sustainability in Cosmetic Dermatology: Moving Toward an Ecologically Responsible Future

Cosmetic dermatology clinics and companies are adopting more environmentally responsible practices to reduce their impact on the planet. This includes switching to biodegradable ingredients, using renewable energy, implementing waste reduction through refillable packaging, and using AI to optimize operations. The industry is also embracing ethical sourcing of ingredients and transparent supply chains through technologies like blockchain to verify sustainability claims and reduce misleading environmental marketing.

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Nutrivigilance: the road less traveled

This paper discusses nutrivigilance, which is the monitoring of side effects from dietary supplements and health products. Unlike medicines, dietary supplements in the US don’t need approval before being sold to consumers. The paper explains what nutraceuticals are, how they’re classified, and the different ways the US and Europe try to keep track of harmful effects. The authors argue that better systems are needed, including more reporting from consumers and better communication between companies, regulators, and healthcare providers.

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Review of Psilocybin Use for Depression among Cancer Patients after Approval in Oregon

Psilocybin, the active compound in certain mushrooms, shows promise as a treatment for depression and anxiety in cancer patients, particularly those nearing end of life. Oregon legalized supervised psilocybin therapy in 2020, making it the first U.S. state to do so. While clinical research shows the treatment can rapidly reduce depression and improve quality of life, the actual rollout has faced challenges including regulatory hurdles, lack of professional standards, and unequal geographic access.

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Current Approaches to Aflatoxin B1 Control in Food and Feed Safety: Detection, Inhibition, and Mitigation

Aflatoxins are poisonous substances made by certain molds that contaminate about a quarter of the world’s food supply and are known carcinogens. This review examines the latest methods for detecting these toxins (from simple lab tests to advanced smartphone-powered devices) and ways to remove or prevent them, including using beneficial bacteria and special plasma treatment. The research shows that combining multiple approaches—detection technology with biological solutions—works best for keeping our food and animal feed safe from these dangerous contaminants.

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Mycotoxin contamination in Malawi: A systematic review of progress and trends in contamination, knowledge, attitude, and practices

This review examines mycotoxin (toxic mold) contamination in Malawi and found that most people—farmers, traders, and health workers—don’t know about these dangerous substances or how to prevent them. Although groundnuts and maize are well-studied, other commonly eaten foods like dried fish and mushrooms have been largely ignored in research. Despite years of efforts to educate communities, awareness remains critically low at about 24.5%, and poverty often forces people to eat contaminated food because it’s cheaper.

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Development of Mycoinsecticides: Advances in Formulation, Regulatory Challenges and Market Trends for Entomopathogenic Fungi

This review explores fungal-based insecticides as environmentally friendly alternatives to chemical pest control. These products use naturally occurring fungi that infect and kill insects through direct contact, making them effective against many crop pests. The review covers different formulation types, product development challenges, and regulatory approval processes in major markets worldwide.

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