nanomedicine – mycolab.ai

Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

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Researchers used mushroom extracts to create tiny zinc oxide particles in an environmentally friendly way. These nanoparticles were tested in mice with liver damage and showed significant protective effects. The particles also demonstrated strong abilities to fight bacteria and fungal infections while acting as powerful antioxidants, suggesting potential use in future medical treatments.

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

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Researchers developed a new way to fight dangerous fungal infections caused by Aspergillus fumigatus by using tiny particles called nanomicelles to deliver genetic material (microRNAs) directly into fungal cells. These microRNAs target and reduce the production of melanin, a protective pigment that helps the fungus resist immune attacks. By weakening this defense, the fungal cells become more vulnerable to the body’s immune system and to stress, offering a novel approach to treat serious fungal infections that have become resistant to standard antifungal drugs.

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

mycolabadmin

Researchers developed a new way to fight dangerous fungal infections caused by Aspergillus fumigatus, which increasingly resists standard antifungal drugs. They used tiny molecules called microRNAs packaged in even tinier delivery vehicles to turn off genes that help the fungus survive. When these microRNAs were introduced, the fungus became much more vulnerable to the body’s immune system and to stress. This novel approach could eventually help treat infections that are otherwise difficult to cure.

Mitigation of radiation-induced esophageal fibrosis by macrophage-targeted phosphatidylserine-containing liposomes with partial PEGylation

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Radiation therapy used to treat esophageal cancer often causes scarring and tissue damage that makes swallowing difficult. Researchers developed special fatty particles called PEGylated phosphatidylserine-containing liposomes that can reduce this scarring by calming down immune cells called macrophages. In studies using animal models and laboratory tests, these particles successfully reduced fibrosis, preserved normal tissue structure, and promoted muscle healing, offering hope for better management of radiation therapy side effects.

Research Topic: nanomedicine

Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

Fungus-targeted nanomicelles enable microRNA delivery for suppression of virulence in Aspergillus fumigatus as a novel antifungal approach

Mitigation of radiation-induced esophageal fibrosis by macrophage-targeted phosphatidylserine-containing liposomes with partial PEGylation