Research Topic: mycoses

Humans vs. Fungi: An Overview of Fungal Pathogens against Humans

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Fungal infections are serious health threats that kill approximately 1.5 million people annually worldwide. This comprehensive review identifies over 280 different fungal species that can infect humans, with Aspergillus being the most dangerous genus. The study provides updated information on how these infections are diagnosed through various methods including cultures, microscopy, and molecular testing, as well as treatment options ranging from traditional antifungal drugs to newer therapies like nanotechnology-based formulations.

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Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

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Researchers studied three dangerous fungi that cause serious infections called mucormycosis. They examined the outer coating of these fungi, called the cell wall, which is made of sugar-like molecules called polysaccharides. When these fungi were exposed to human immune cells, they triggered strong inflammatory responses. Understanding these fungal components could help develop better treatments and vaccines for this life-threatening infection.

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Frequency, Interval, and Patient Factors Associated With Recurrence of Disseminated Cutaneous Coccidioidomycosis

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This study looked at how often a serious fungal skin infection called coccidioidomycosis comes back after treatment. Researchers found that about 25% of patients experienced at least one recurrence after stopping antifungal medications, with the average time before it returned being 14 months. Some patients had multiple recurrences, and most of the time the infection returned to the same location on the body.

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